摘要
目的探究脂蛋白a与同型半胱氨酸联合检测在脑卒中诊断和预后判断中的应用价值。方法收集2016年1月~2018年12月我院脑卒中患者86例,其中脑出血40例,脑梗死患者46例,另选择院内同期接受健康体检者40例。比较各组脂蛋白a及同型半胱氨酸水平,对发生脑卒中的危险因素予以相关性分析。结果与对照组比较,脑卒中组脂蛋白a以及同型半胱氨酸较高,差异有统计学意义(P<0.05);脑梗死组与脑出血组脂蛋白a以及同型半胱氨酸相比差异无统计学意义(P>0.05)。与对照组相比,脑卒中组脂蛋白a、同型半胱氨酸阳性率及联合检测阳性率较高,差异有统计学意义(P<0.05);脑卒中组联合检测阳性率较单一指标阳性率高,差异有统计学意义(P<0.05)。结论脂蛋白a与同型半胱氨酸是脑卒中的有效预测因子,可以作为脑卒中的诊断、预后指标,两者联合检测阳性率较单一检测高,检测效果优于单一检测。
Objective To explore the value of combined detection of lipoprotein a(Lpa)and homocysteine(Hcy)in the diagnosis and prognosis of stroke.Methods 86 patients with stroke treated in our hospital from January 2016 to December 2018 were collected,including 40 with cerebral hemorrhage,46 with cerebral infarction.40 healthy people examined in our hospital in the same period were enrolled as the control group.The levels of Lpa and Hcy were compared in each group,and the risk factors of stroke were analyzed.Results Compared with the control group,the level of Lpa and Hcy in the stroke group was higher,and the difference was statistically significant(P<0.05);there was no difference in the level of Lpa and Hcybetween the cerebral infarction group and cerebral hemorrhage group(P>0.05).Compared with the control group,the positive rate of Lpa,Hcy and combined detection in stroke group were higher,and the difference was statistically significant(P<0.05);the positive rate of combined detection in stroke group was higher than that of single index,and the difference was statistically significant(P<0.05).Conclusion Lpa and Hcy are effective predictors of stroke,which can be used as indicators of diagnosis and prognosis of stroke.The positive rate of combined detection is higher than that of single index,and the effect is better as well.
作者
许朝旭
李旭萍
XU Zhaoxu;LI Xuping(Department of Laboratory Medicine,He Xian Memorial Hospital,Panyu District,Guangzhou 511400,China;Dashi Street Community Health Service Center,Panyu District,Guangzhou 511430,China)
出处
《中国医药科学》
2020年第5期165-167,共3页
China Medicine And Pharmacy
