摘要
在无配体条件下,以聚乙二醇(PEG-400)和水为反应介质,醋酸钯为催化剂,卤代代芳烃和芳基硼酸通过交叉偶联反应合成一系列联苯类化合物(3a^3h),其结构经1H NMR和13C NMR表征,交叉偶联产率为30%~99%。PEG和水作为反应溶剂减少了对环境污染,实现了偶联反应的绿色化。
Using PEG-400/H2O as the reaction medium and Pd(OAc)2 as the catalyst,a series of biphenyl compounds(3a^3h)were synthesized by the cross-coupling reactions of aryl halides with arylboronic acids under ligand-free conditions.The structures were characterized by 1H NMR and 13C NMR,and the yield of the cross-coupling were 30%~99%.PEG/H2O as reaction solvent can reduce environmental pollution and realize green coupling reaction.
作者
匡仁云
张振兴
黄翔
沈玉君
邹红
谢宝星
唐伯孝
KUANG Ren-yun;ZHANG Zhen-xing;HUANG Xiang;SHEN Yu-jun;ZOU Hong;XIE Bao-xin;TANG Bo-xiao(School of Chemistry and Chemical Engineering,Ji’an,Jiangxi 343009,China;The key Laboratory of Coordination Chemistry of Jiangxi Province,and Institute of Applied Chemistry,Jinggangshan University,Ji’an,Jiangxi 343009,China)
出处
《井冈山大学学报（自然科学版）》
2020年第1期25-29,共5页
Journal of Jinggangshan University (Natural Science)
基金
国家自然科学基金项目(21563015)
江西省教育厅科技计划项目(GJJ170656)
国家级大学生创新创业训练计划项目(201910419008)。
