摘要
目的分析武汉江岸方舱医院新型冠状病毒肺炎(COVID-19)病例临床特征、转归,为本病的防治提供参考。方法回顾性分析2020年2月12日至2020年3月8日,武汉江岸方舱医院收治的472例COVID-19患者的临床资料,对比出院及转院患者的年龄、首发临床症状、胸部CT表现、合并症等方面是否存在差异。结果472例患者中,男(215例)女(257例)的比例是1∶1.2。首发临床症状以发热(75.4%)、干咳(50.0%)、乏力(20.1%)为主。87例(18.4%)患者合并慢性基础疾病。37例(7.8%)核酸阳性的患者没有任何临床症状,其中2例转院治疗。31例(6.5%)核酸阳性的患者胸部CT没有任何异常,均出院。57例(12.1%)患者病情加重,转院治疗,无死亡病例。出院组和转院组比较,在发热、干咳、胸闷憋气、周身酸痛、腹泻、寒战方面差异有统计学意义(P<0.05)。在发热为首发的临床症状病例中,两组在低热、高热、超高热方面差异有统计学意义(P<0.05)。出院患者和转院患者比较,在胸部CT表现病灶呈双肺弥漫性分布、病灶累及单个肺叶、多发病灶、单发病灶及没有任何异常方面差异有统计学意义(P<0.05)。46例患者行新型冠状病毒特异性抗体(IgG、IGM)检测,其中IgM、IgG均阳性8例,IgM阴性、IgG阳性38例,两个抗体均阴性0例。结论年龄大、基础疾病多、胸部CT表现为弥漫性病变,首发临床症状伴有发热(尤其是高热)、干咳、胸闷憋气、周身酸痛、腹泻、寒战的此类患者是COVID-19的高危人群,且易进展为(危)重患者。
Objective To analyze the clinical characteristics and outcome of coronavirus disease 2019(COVID-19)in Wuhan Jiangan Makeshift(Fangcang)Hospital for reference in prevention and treatment of this disease.Methods Retrospective analysis was conducted on the clinical data of 472 COVID-19 patients admitted to Wuhan JiangAn Makeshift(Fangcang)Hospital from February 12 to March 8,2020 to see whether there were differences among COVID-19 patients,discharged and transferred patients in terms of the age,first clinical symptoms,chest CT findings and complications.Results Of 472 patients,the ratio of males(215)to females(257)was 1∶1.2.The first clinical symptoms were mainly fever(75.4%),dry cough(50.0%)and fatigue(20.1%).There were 87 patients(18.4%)with chronic basic diseases.A total of 37(7.8%)patients with positive nucleic acid showed no clinical symptoms,and two of them were transferred for further treatment.Totally 31 patients(6.5%)with positive nucleic acid had no abnormal chest CT findings and were discharged from the hospital.And 57 patients(12.1%)became sicker and were transferred for further treatment.No deaths were reported.There were statistically significant differences between the discharged and the transferred patients in fever,dry cough,chest tightness,soreness,diarrhea and chills(P<0.05).Among the patients having clinical symptoms with fever as the first symptom,there were statistically significant differences in terms of low fever,high fever and ultra-high fever(P<0.05).There were statistically significant differences between discharged patients and transferred patients in terms of the diffuse distribution of chest CT lesions in both lungs,the involvement of lesions in a single lobe,multiple lesions,single lesion and no abnormalities(P<0.05).Novel coronavirus specific antibodies(IgG,IGM)were tested in 46 patients,of which eight cases were tested positive for IGM and IgG,38 cases were tested negative for IGM and positive for IgG,and 0 was tested negative for both antibodies.Conclusion COVID-19 high-risk pop
作者
白敏
刘献强
吴伟强
孙凯
黄旭
靳怀宗
Bai Min;Liu Xianqiang;Wu Weiqiang;Sun Kai;Huang Xu;Jin Huaizong(Department of Respiratory Medicine,Tianjin Hongqiao Hospital,Tianjin 300131,China;Department of Cardiology,Tianjin Hongqiao Hospital,Tianjin 300131,China;Department of Emergency,Tianjin Hongqiao Hospital,Tianjin 300131,China;Department of Neurosurgery,Tianjin Hongqiao Hospital,Tianjin 300131,China;Department of Critical Care Medicine,Tianjin Hongqiao Hospital,Tianjin 300131,China;Wuhan Jiangan Makeshift(Fangcang)Hospital,Whhan 430000,China;Department of Orthopedics,Tianjin Beichen Hospital of Traditional Chinese Medicine,Tianjin 300400,China)
出处
《临床荟萃》
CAS
2020年第4期297-301,共5页
Clinical Focus
关键词
新型冠状病毒肺炎
方舱医院
临床特征
COVID-19
Makeshift(Fangcang)hospital
Clinical characteristics
