摘要
目的:观察三焦次第疗法对阳虚型慢性心力衰竭患者的临床疗效。方法:将100例慢性心力衰竭患者随机分为对照组50例,给予常规西药治疗;治疗组50例,在给予对照组用药的同时给予三焦次第疗法中药口服。两组患者疗程均为3周,观察治疗前后的生存质量量表(LHFQ)、匹兹堡睡眠指数(PSQI)、6min步行试验、心功能分级变化、随访期间再入院率、死亡率、左室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、NT-proBNP、hs-CRP、ET-1的变化。结果:经治疗后,治疗组患者的LHFQ评分、PSQI、心功能分级、左心室舒张末期内径、左心室收缩末期内径、NT-proBNP、hs-CRP、ET-1均低于对照组(P<0.05),治疗组患者6min步行距离、左室射血分数均高于对照组(P<0.05)。结论:三焦次第疗法对慢性心力衰竭患者能够提高生存质量,提高睡眠质量,增加运动耐量,改善心功能,降低患者NT-proBNP、hs-CRP及ET-1水平,增加左室射血分数,降低左室舒张末期内径及左室收缩末期内径。
Objective:To observe the clinical curative effect of Sanjiao Regular Sequence therapy in patients with Yang deficiency syndrome of chronic heart failure type.Methods:100 patients with chronic heart failure were randomly divided into 50 cases of in controlled group and were given conventional western medicine treatment;50 cases of in treatment group were given drugs used in the controlled group and Chinese medicine treatment of Sanjiao Regular Sequence therapy.The course of treatment in the two groups was 3 weeks.Observated changes of living with heart failure questionnaire(LHFQ) scores,Pittsburgh sleep quality index(PSQI) scores,6-minunction classification,eadmission rate,mortality rate,left ventricular ejection fractionute walk test distance,heart f(LVEF),left ventricular end-diastolic internal diameter(LVEDD),left ventricular end-systolic dimension(LVESD),NT-proBNP,hs-CRP and ET-1.And evaluated the safety of treatment methods by changes of the blood routine,urine routine,stool routine,liver function,renel function and electrocardiogram before and after treatment.Results:After treatment,the LHFQ score,PSQI,cardiac function classification,LVEDD,LVESD,NT-proBNP,hs-CRP,ET-1 of the treatment group were all lower than those of the controlled group(P < 0.05).The 6-minute walking distance and LVEF in the treatment group were all higher than those of the controlled group(P < 0.05).Conclusion:Sanjiao Regular Sequence therapy on patients with chronic heart failure can improve the quality of life,improve the quality of sleep,heart increase the amount of exercise tolerance,improve heart function,reduce the level of NT-proBNP,hs-CRP and ET-1,increase left ventricular ejection fraction,decrease left ventricular end-diastolic internal diameter and left ventricular end-systolic dimension.
作者
陀鹏
唐农
李成林
王庆高
陈炜
陆玉薇
叶仕晟
TUO Peng;TANG Nong;LI Cheng-lin(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning Guangxi 530023,China;Guangxi University of Traditional Chinese Medicine,Nanning Guangxi 530001,China)
出处
《四川中医》
2020年第3期112-115,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
广西中医基础研究重点实验室系统课题(编号:15-140-32-02)
广西医学高层次骨干人才培养“139”计划项目(编号:桂卫科教发[2014]14号)
广西重点研发计划(编号:桂科AB16380324)
广西中医药大学杰出青年基金项目(编号:2016JQ001)。
关键词
三焦次第
心力衰竭
临床研究
Sanjiao regular sequence
Heart failure
Clinical study
