摘要
目的研究体液免疫功能与hs-CRP检验应用在支原体肺炎患儿检验中的意义。方法选取2017年3月~2019年3月在我院接受治疗的支原体肺炎患儿80例,其中重症患儿40例,将其划分为A组,为轻症患儿40例,将其划分为B组,再抽取同时期的40例健康儿童作为对照组,对选取支原体肺炎患儿以及健康儿童开展体液免疫功能检测以及超敏C反应蛋白检测(hs-CRP),比较各项观察指标,综合分析其在支原体肺炎患儿诊断中的意义。结果(1)A组患儿以及B组患儿的IgG、IgM水平与对照组健康儿童进行比较均明显较高(P<0.05),IgA水平与对照组健康儿童进行比较则明显较低(P<0.05)。A组患儿的IgG、IgM水平与B组比较明显较高(P<0.05),IgA水平与B组比较则明显较低(P<0.05)。(2)A组患儿与B组患儿的hs-C R P、肿瘤坏死因子(T N F-α)、白细胞介素-6(I L-6)水平与对照组比较明显较高(P<0.05),A组患儿的hs-CRP、TNF-α、IL-6水平与B组比较显著较高(P<0.05)。结论支原体肺炎患儿的诊断中体液免疫功能以及超敏C反应蛋白检测均占据重要地位,临床上应当合理使用,准确把握患儿的病情,从而开展安全有效的治疗方案,促进患儿的身体恢复。
Objective To study the significance of humoral immune function and hs-CRP test in children with mycoplasma pneumonia.Methods 80 children with mycoplasma pneumonia who were treated in our hospital from March 2017 to March 2019 were selected.40 children with severe mycoplasma pneumonia were set as group A and 40 children withmild mycoplasma pneumoniawere set as group B.40 healthy children in the same period were selected as the control group.Humoral immune function and hypersensitive C-reactive protein(hs-CRP)in children with mycoplasma pneumonia and healthy children were detected.Observation indexes were compared and its significance in the diagnosis of children with mycoplasma pneumonia was comprehensively analyzed.Results(1)The levels of IgG and IgM of children in group A and group B were significantly higher than those of healthy children in control group(P<0.05).But IgA level was significantly lower than that in control group(P<0.05).The levels of IgG and IgM in group A were significantly higher than those in group B(P<0.05),while the level of IgA was significantly lower than that in group B(P<0.05).(2)The levels of hs-CRP,tumor necrosis factor(TNF-α)and interleukin-6(IL-6)in group A and group B were significantly higher than those in the control group(P<0.05).The levels of hs-CRP,TNF-α and IL-6 in group A were significantly higher than those in group B(P<0.05).Conclusion The detection of humoral immune function and high-sensitivity C-reactive protein occupies an important positionin the diagnosis of children with mycoplasma pneumonia.Clinically,it should be used reasonably to accurately grasp the condition of the child,so as to carry out safe and effective treatment programs to promote the recovery of the children.
作者
郭琳琳
GUO Linlin(Department of Laboratory,Hedong Branch,Guangzhou First People’s Hospital,Guangdong,Guangzhou 510380,China)
出处
《中国医药科学》
2020年第3期174-177,共4页
China Medicine And Pharmacy
关键词
体液免疫功能
超敏C反应蛋白
支原体肺炎
应用价值
Humoral immune function
Hypersensitive C-reactive protein
Mycoplasma pneumonia
Clinical significance
