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糖尿病足下肢截肢的危险因素分析 被引量:5

Risk factors of lower limb amputation in diabetic foot
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摘要 目的评估糖尿病足下肢截肢的发病率,探讨其相关危险因素。方法回顾性分析2015年1月至2018年12月在温州市中医院就诊的糖尿病足患者135例次的临床资料,按是否截肢分为截肢组25例、非截肢组110例,对两组的病例资料包括年龄、性别、糖尿病病程、合并症(包括高血压、冠心病)、糖尿病足分级、白细胞计数、糖化血红蛋白(HbA1c)、C反应蛋白、血脂四项等指标进行比较。结果截肢率为18.5%(25/135)。截肢组的周围血管病变(PAD)患病率为68.0%,Wangner分级轻/重比例为6/19,均高于非截肢组,差异均有统计学意义(χ2=5.938,P=0.014;χ2=48.316,P=0.012);非截肢组与截肢组的实验室检查相关指标[白细胞计数(7.9±2.1)×109/L比(9.1±2.3)×109/L,HbA1c(8.5±2.5)%比(9.3±2.4)%,C反应蛋白(4.0±1.0)mg/L比(7.0±1.0)mg/L,高密度脂蛋白胆固醇(HDL-C)(1.0±0.3)mmol/L比(0.8±0.4)mmol/L]差异均有统计学意义(t=-2.900、2.210、-4.461、2.510,均P<0.05)。结论PAD是糖尿病足患者截肢的危险因素,Wagner分级越高、HbA1c、白细胞计数和C反应蛋白越高,则糖尿病足患者截肢的风险越高。
作者 林奇仲 钱吹 Lin Qizhong;Qian Chui(Department of Emergency Surgery,Wenzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine,Wenzhou,Zhejiang 325000,China)
出处 《中国基层医药》 CAS 2020年第3期348-350,共3页 Chinese Journal of Primary Medicine and Pharmacy
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