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血清脂联素与2型糖尿病大血管并发症的相关性研究 被引量:4

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摘要 目的探讨血清脂联素水平与2型糖尿病大血管并发症的相关性。方法将所选的2型糖尿病患者106例分为单纯2型糖尿病组和2型糖尿病合并大血管病变组。对所有受试者测量身高、体质量、血压,同时分别测定三酰甘油,总胆固醇,低密度脂蛋白胆固醇,高密度脂蛋白胆固醇,糖化血红蛋白、空腹血糖、高敏C-反应蛋白、血清脂联素水平、空腹胰岛素、颈动脉内膜中层厚度等。结果两组间血清脂联素水平差异有统计学意义(P<0.05),Logistic回归进行多因素分析显示调整年龄、性别、BMI及高敏C反应蛋白等因素后血清脂联素与高密度脂蛋白显著正相关(P<0.05),与收缩压及颈动脉内膜中层厚度呈负相关(P<0.05)。结论血清脂联素水平与2型糖尿病大血管并发症的发生发展有关,其在糖尿病动脉粥样硬化过程中可能起重要作用。
出处 《中国临床保健杂志》 CAS 2013年第6期644-646,共3页 Chinese Journal of Clinical Healthcare
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