摘要
目的通过观察不同人群流行性感冒(甲型)的临床特点,提高对流行性感冒(甲型)诊治的认识。方法收集2018年12月-2019年3月医院呼吸内科和感染二科住院的101例甲型流感病毒核酸检测阳性患者的资料,回顾性分析不同人群的临床症状、实验室检查结果、并发症及治疗转归。结果本组患者中一般人群(A组) 47例,重症流感高危人群(B组) 54例,B组中合并艾滋病患者(B1组) 10例,妊娠患者(B2组) 8例,合并慢性疾病患者(B3组) 36例。所有患者中发热者82例(占81. 19%),其中A组40例,B组42例,A、B两组间无统计学差异。所有患者中血白细胞下降22例(占21. 78%),其中A组血常规白细胞减少10例,B组12例;所有患者血淋巴细胞下降58例(占57. 43%),其中A组血淋巴细胞减少22例,B组36例。两组间白细胞减少无统计学差异,淋巴细胞减少有统计学差异。所有患者流感病毒A抗原阳性31例(占30. 69%),其中A组15例,B组16例,两组间无统计学差异。本组患者合并肺炎为64例(占63. 37%),其中A组27例,B组37例,B组合并肺炎发生率更高。本组患者服用奥司他韦治疗且有效者占91. 09%。结论不同人群甲型流行性感冒均多见发热症状,血常规淋巴细胞减少明显,流感抗原A阳性率偏低,流感患者并发症中肺炎发生率高,其中重症流感高危人群为甚。奥司他韦治疗A型流行性感冒效果好。
Objective To enhance the knowledge of diagnosis of influenza( type A) through observing the clinical characteristics. Methods One hundred and one cases were recruited from respiratory medicine department and infection medicine department of GZ Eight People’s Hospital,which were diagnosed as influenza A from Jan,2018 to Dec,2019,and the nucleic acid test of influenza A virus were positive in all the patients. The clinical features,test results of lab,complication and treatment outcome were eetrospectively analyzed. Results In the 101 cases,47 cases( group A) were common,and 54 cases( group B) were severe. In group B,there were 10 cases complicated with AIDS,10 cases with encyesis,and 36 cases with chronic disease. In 82 cases( 81. 19%),the patients had the feverous symptom,and 40 cases in group A,42 cases in group B. However,between the groups,there was no statistical difference. 22 cases presented the reduction of white blood cells. For group A,10 cases showed the WBC reduction in routine blood test. For group B,there were 12 cases in same situation. 58 cases( 57. 43%) presented the blood lymphocytes reduction. In group A,22 cases presented lymphocytes reduction,and in group B it was 36 cases. There was no significant difference between the two groups in the WBC reduction,but significant difference in lymphocytes reduction. 64 cases( 63. 37%) were complicated with pneumonia,27 cases from group A,37 cases from group B. Group B showed the higher pneumonia complication. It was effective for 91. 09% patients by taking Oseltamivir. Conclusion The feverous symptom is very normal in influenza A for different patients,the WBC reduction in routine blood test is also very obvious,and antigen A of influenza has low positive rate. In the complication of influenza,the pneumonia occurs in high probability,especially for server influenza patients. Oseltamivir has a good effect on influenza.
作者
彭平
彭辉
陈沐
巫培连
PENG Ping;PENG Hui;CHEN Mu;WU Peilian(Guangzhou Eight People’s Hospital,Guangzhou Medical University,Guangzhou 510060,China)
出处
《现代医院》
2020年第2期267-269,共3页
Modern Hospitals
基金
广东省医学科研基金(A2014572)。
