摘要
转化医学学会(TSM)2017年发表了《男性不育症精子DNA碎片检测临床实践指南》(以下简称《指南》)。《指南》阐述了精子DNA碎片(SDF)的检测方法、检测适应症、精子DNA碎片指数(DFI)结果分析,及其与辅助生殖预后关系等方面。本文通过对《指南》的解读,旨在指导临床医师和检验人员规范SDF的检测和应用,尤其是对DFI的结果进行客观分析。
The Society for Translational Medicine(TSM)published the“Clinical Practice Guidelines for Sperm DNA Fragmentation Testing in Male Infertility”(hereinafter referred to as the“Guide”)in 2017.The“Guide”discussed the evaluation,diagnosis&detection of indications of sperm DNA fragments(SDF),result analysis of sperm DNA fragmentation index(DFI)and its relationship with assisted reproductive outcomes.This paper aims to guide clinicians and inspectors to standardize SDF detection and application,as well as objective analysis of DFI results,through the interpretation of the“Guide”.
作者
高庆和
晏斌
刘煜
刘胜京
付建华
GAO Qing-he;YAN Bin;LIU Yu;LIU Sheng-jing;FU Jian-hua(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091)
出处
《生殖医学杂志》
CAS
2020年第3期416-421,共6页
Journal of Reproductive Medicine
基金
国家自然科学基金面上项目(81473527)
国家自然科学基金青年项目(81703929)
关键词
精子DNA碎片
精子DNA碎片指数
转化医学学会
男性不育
指南
Sperm DNA fragments(SDF)
Sperm DNA fragmentation index(DFI)
Society for translational medicine
Male infertility
Guideline