摘要
目的:探讨分析双水平气道正压通气(BiPAP)联合纳洛酮(NLX)对中重度老年慢性阻塞性肺疾病(COPD)稳定期患者肺功能及血气分析的影响。方法:选取2017年1月-2018年12月笔者所在医院筛选出88例中重度老年COPD患者,将其随机分为对照组和观察组,每组44例。对照组进行一系列常规性治疗,观察组在此基础上联合采用BiPAP和NLX进行治疗。比较两组患者治疗前后肺功能(FEV1、FVC及PEF)及血气分析情况(pH值、PaO2及PaCO2)。结果:治疗前两组各项肺功能指标及血气分析指标比较差异无统计学意义(P>0.05),治疗后观察组肺功能指标及血气分析指标均优于对照组,差异均有统计学意义(P<0.05)。结论:BiPAP联合NLX能显著改善中重度老年COPD稳定期患者的肺功能和血气分析指标,疗效显著,值得临床推广。
Objective:To discuss and analyze the effects of BiPAP and NLX on the pulmonary function and blood gas analysis in moderate and severe COPD patients at stable stage in elderly.Method:From January 2017 to November 2018,88 old patients with moderate and severe COPD were selected from our hospital.They were randomly divided into the control group and the observation group,with 44 cases in each group.Patients in control group accepted conventional treatment,and the observation group were given BiPAP and NLX.The pulmonary function(FEV1,FVC and PEF)and blood gas analysis including pH,PaO2 and PaCO 2 were analyzed and compared.Result:There was no significant difference in pulmonary function index and blood gas analysis index between the two groups before treatment(P>0.05).After treatment,the pulmonary function index and blood gas analysis index in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The combination of BiPAP and NLX is an effective treatment to moderate and severe COPD patients at stable stage in elderly.
作者
黄俊铭
魏刘法
HUANG Junming;WEI Liufa(Guangzhou Liwan District People’s Hospital,Guangzhou 510370,China)
出处
《中外医学研究》
2020年第1期15-17,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
