摘要
目的探讨上消化道黏膜病变的病理类型和临床特点的关系,为临床诊治该病提供参考依据。方法回顾性分析2014年1月~2018年12月我院收集的9659例上消化道黏膜活检病理诊断结果,观察胃炎、息肉、溃疡和肿瘤病变与年龄、性别、幽门螺杆菌(Hp)感染情况的关系。结果①胃炎:不同年龄段慢性炎症、萎缩、肠化、上皮内瘤变人数比较,差异有统计学意义(P<0.05)。女性慢性炎症轻度和中度人数高于男性,差异有统计学意义(P<0.05);不同性别萎缩、肠化、上皮内瘤变人数比较,差异无统计学意义(P>0.05);慢性炎症、萎缩、肠化、上皮内瘤变不同严重程度Hp(+)人数高于Hp(-),差异均有统计学意义(P<0.05)。②息肉:不同年龄段胃息肉、贲门息肉、食道息肉病变人数比较,差异有统计学意义(P<0.05)。女性胃息肉、食道息肉人数高于男性,差异有统计学意义(P<0.05);不同性别贲门息肉、十二指肠息肉人数比较,差异无统计学意义(P>0.05)。胃息肉、贲门息肉不同类型Hp(+)人数高于Hp(-),差异有统计学意义(P<0.05);食道息肉、十二指肠息肉HP感染人数比较,差异无统计学意义(P>0.05)。③溃疡和肿瘤病变:不同年龄段胃溃疡、胃癌、食管癌人数比较,差异有统计学意义(P<0.05);不同年龄段贲门溃疡人数比较,差异无统计学意义(P>0.05)。男性胃溃疡、食道溃疡、贲门溃疡、胃癌、食管癌人数高于女性,差异有统计学意义(P<0.05)。胃溃疡、食道溃疡、贲门溃疡、胃癌、食管癌Hp(+)人数高于Hp(-),差异有统计学意义(P<0.05)。结论轻度慢性胃炎好发于青中年性,息肉、溃疡、肿瘤病变好发于中老年人,轻度慢性胃炎、息肉病变好发于女性,溃疡和肿瘤病变好发于男性,胃炎相关病变、息肉、溃疡、肿瘤与Hp感染密切相关。
Objective To explore the relationship between pathological types and clinical characteristics of upper gastrointestinal mucosal lesions,and to provide reference basis for clinical diagnosis and treatment of the disease.Methods A retrospective analysis of 9659 cases of upper gastrointestinal mucosal biopsy collected in our hospital from January 2014 to December 2018 was performed to observe the gastroenteritis,polyps,ulcers,tumor lesions,age,gender,and Helicobacter pylori(Hp)infection relationship.Results(1)Gastritis:There were significant differences in the number of chronic inflammation,atrophy,intestinalization,and intraepithelial neoplasia at different ages(<0.05).The number of women with mild and moderate chronic inflammation was higher than that of men,the difference was statistically significant(<0.05);there was no significant difference in the number of atrophy,intestinalization,and intraepithelial neoplasia between different genders(>0.05);Chronic inflammation,atrophy,intestinalization,and intraepithelial neoplasia were more severe in Hp(+)than Hp(-),the differences were statistically significant(<0.05).(2)Polyps:There were statistically significant differences in the number of lesions of gastric polyps,cardia polyps,and esophageal polyps at different ages(<0.05).The number of women with gastric polyps and esophagus polyps was higher than that of men,the difference was statistically significant(<0.05).There was no significant difference in the number of different genders of cardia polyps and duodenal polyps(>0.05).The number of different types of Hp(+)in gastric polyps and cardia polyps was higher than Hp(-),the difference was statistically significant(<0.05).There was no significant difference in HP infection among esophageal polyps and duodenal polyps(>0.05).(3)Ulcers and tumor lesions:There was a statistically significant difference in the number of gastric ulcers,gastric cancer,and esophageal cancer at different ages(<0.05);there was no statistically significant difference in the number of cardiac ulc
作者
陶源
徐俊林
张艳
王博
王立颖
张琦圣
TAO Yuan;XU Jun-lin;ZHANG Yan;WANG Bo;WANG Li-ying;ZHANG Qi-sheng(Department of Spleen and Gastroenterology,Department of Pathology,Beijing 102200,China;Department of Spleen and Gastroenterology,Changping District Traditional Chinese Medicine Hospital,Beijing 102200,China)
出处
《医学信息》
2020年第2期125-128,135,共5页
Journal of Medical Information
关键词
上消化道黏膜病变
慢性胃炎
幽门螺杆菌
Upper gastrointestinal mucosal lesions
Chronic gastritis
Helicobacter pylori
