摘要
目的探讨多囊卵巢综合征(polycystic ovary syndrome,PCOS)患者经CT、MRI联合三维能量多普勒超声的表现特征与其病理分型及内分泌功能的关系。方法选取PCOS患者(PCOS组)128例和健康体检者(对照组)50例。所有研究对象均进行三维能量多普勒超声检查,比较2组卵巢面积(total area,TA)、卵巢体积(ovary volume,2D-OV)、间质面积(interstitial area,SA)、卵巢间质动脉搏动指数(pulsation index,PI)和阻力指数(resistance index,RI);检测2组黄体生成素(luteinizing hormone,LH)、卵泡刺激素(follicle stimulating hormone,FSH)、LH/FSH、睾酮(testosterone,T)、雌二醇(estradiol,E 2)及胰岛素抵抗指数(Homeostasis model-insulin resistance,HOMA-IR);分析超声参数与患者PCOS病理分型的相关性。按照随机数字表法将PCOS患者分为CT组和MRI组,每组64例,分别进行CT和MRI检查,比较2组特征差异。结果PCOS组TA、2D-OV、SA均显著高于对照组,PI和RI均显著低于对照组(P<0.05)。PCOS组LH、LH/FSH、T、E 2和HOMA-IR水平均显著高于对照组(P<0.05),2组FSH水平差异无统计学意义(P>0.05)。2D-OV与LH/FSH、HOMA-IR呈正相关,TA、SA与T呈正相关(P<0.05)。多因素Logistic回归分析,结果表明,TA、2D-OV、PI和RI是PCOS病理分型的影响因素。CT平扫检查PCOS时可见囊性病灶,壁薄光滑,呈水样密度;增强扫描时病灶间质呈轻或中度强化。MRI平扫时卵巢区分布多个囊性肿物,外形光滑;增强扫描时病灶间质显示中或高等信号。结论PCOS患者超声特征和内分泌指标与健康人存在显著差异,且二者之间存在一定相关性,卵巢超声特征能够在一定程度上反映患者内分泌功能,且对判断患者病理分型具有重要意义。
Objective To investigate the relationship between CT,MRI and three-dimensional power Doppler ultrasound in patients with polycystic ovary syndrome polycystic ovary syndrome(PCOS)and its pathological type and endocrine function.Methods A total of 128 PCOS patients were enrolled as the PCOS group.Fifty healthy subjects were selected as the control group.Three-dimensional power Doppler ultrasonography was used to observe the characterization of all subjects.The area total area(TA),ovarian volume(2D-OV),interstitial area(SA),ovarian interstitial pulsation index(PI)and resistance index(RI)were compared between two groups;the luteinizing hormone(LH),follicle stimulating hormone(FSH),LH/FSH,testosterone(T),estradiol(E 2)and Homeostasis model-insulin resistance(HOMA-IR)were detected and compared between two groups.The relevance of ultrasound parameters and pathological classification of patients were analyzed.The PCOS patients were further divided into CT group and MRI group according to the random number table method,with 64 patients in each group.The CT and MRI were performed in CT group and MRI group,respectively.The differences between the two groups were compared.Results TA,SA and 2D-OV in PCOS group were significantly higher than those in control group,PI and RI were significantly lower than those in control group(P<0.05).The levels of LH,LH/FSH,T,E 2 and HOMA-IR in PCOS group were significantly higher than those in the control group(P<0.05).2D-OV was positively correlated with LH/FSH,HOMA-IR,TA,SA was positively correlated with T(P<0.05).Logistic regression analysis showed that TA,2D-OV,PI,RI were independent risk factors affecting the pathological classification of PCOS.The performance characteristics of CT and MRI detection were significant difference.Conclusion There are significant differences in the ultrasound characteristics and endocrine indexes between PCOS patients and control group,and there is a certain correlation between them.The ovarian ultrasound characteristics can reflect the endocrine function of
作者
许莉
赵波
赵萍
XU Li;ZHAO Bo;ZHAO Ping(Department of Ultrasound,General Hospital of Jianghan Oilfield,Hubei Province,Qianjiang 433124,China)
出处
《河北医科大学学报》
CAS
2020年第2期196-199,218,共5页
Journal of Hebei Medical University
关键词
多囊卵巢综合征
超声检查
体层摄影术
磁共振成像
polycystic ovary syndrome
ultrasonography
tomography
magnetic resonance imaging
