摘要
目的:探讨纳米银联合重组牛碱性成纤维细胞生长因子(rb-bFGF)凝胶治疗烧伤患者的临床疗效。方法:随机将2015年1月~2017年12月治疗烧伤的84例患者分为两组,A组采用纳米银治疗,B组在此基础上联合rb-bFGF凝胶治疗,比较两组的治疗效果。结果:B组浅Ⅱ度创面、深Ⅱ度创面愈合时间均明显短于A组,且B治疗后1周、2周、3周的愈合率与治疗总有效率明显高于A组,创面感染发生率明显低于A组,差异有统计学意义(P<0.05)。结论:烧伤患者采用rb-bFGF凝胶联合纳米银治疗,有助于缩短创面愈合时间,降低创面感染率,促进烧伤创面愈合。
Objective:To discuss the clinical efficacy of nano-silver combined with recombinant bovine basic fibroblast growth factor(rb-bFGF)gel in the treatment of burn patients.Methods:Eighty-four burned patients were randomly divided into two groups from January 2015 to December 2017.Group A was treated with silver nanoparticles and group B was treated with rb-bFGF gel.Results:The healing time of superficial second degree wound and deep second degree wound in group B was significantly shorter than that in group A,and the healing rate and total effective rate at 1,2 and 3 weeks after treatment in group B were significantly higher than that in group A,and the incidence of wound infection was significantly lower than that in group A(P<0.05).Conclusion:The treatment of rb-bFGF gel combined with nano-silver on burn patients can shorten the wound healing time,reduce the infection rate and promote the healing of burn wounds.
作者
海艳丽
Hai Yanli(Department of Burn,Pingdingshan the 152nd Central Hospital of the People's Liberation Army of China,Pingdingshan 467000)
出处
《数理医药学杂志》
2020年第3期432-433,共2页
Journal of Mathematical Medicine