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乳腺癌前哨淋巴结转移的相关因素分析及病理学研究 被引量:2

Analysis of Related Factors and Pathology of Sentinel Lymph Node Metastasis in Breast Cancer
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摘要 目的探究乳腺癌前哨淋巴结转移的相关因素。方法回顾性分析162例前哨淋巴结活检技术的乳腺癌患者的临床资料,对乳腺癌临床病理指标与前哨淋巴结转移之间的关系进行因素分析。结果前哨淋巴结阳性共83例,前哨淋巴结阴性共79例。2组间的年龄、性别组成、体重指数、吸烟史和饮酒史等的差异均无统计学意义(P>0.05)。原发肿瘤位置、活检方式与前哨淋巴结转移无关(P>0.05),但病理类型与前哨淋巴结转移有关。随着肿瘤的变大,灵敏度、特异性也随之升高。多元Logistic回归分析显示,肿瘤直径和病理类型是影响前哨淋巴结转移的独立危险因素(P<0.05)。结论乳腺癌前哨淋巴结转移考虑与肿瘤大小及病理类型相关,但具体病例需具体分析后考虑是否可行前哨淋巴结活检术。 Objective To explore the related factors of sentinel lymph node metastasis in breast cancer.Methods The clinical data of 162 patients with breast cancer who underwent sentinel lymph node biopsy were retrospectively analyzed.The relationship between clinicopathological parameters of breast cancer and sentinel lymph node metastasis was analyzed.Results There were 83 positive sentinel lymph nodes and 79 negative sentinel lymph nodes.There were no significant differences in age,sex composition,body mass index,smoking history and drinking history between the 2 groups(P>0.05).The location and biopsy method of primary tumors were not related to sentinel lymph node metastasis(P>0.05),but the pathological type was related to sentinel lymph node metastasis.With the increase of tumors,the sensitivity and specificity increase.Multivariate logistic regression analysis showed that tumor diameter and pathological type were independent risk factors for sentinel lymph node metastasis(P<0.05).Conclusion Sentinel lymph node metastasis in breast cancer is related to tumor size and pathological type,but the feasibility of sentinel lymph node biopsy should be considered after specific case analysis.
作者 张卫 黄彬 沈丽 ZHANG Wei;HUANG Bin;SHEN Li(Zhangjiagang Aoyang Hospital,Zhangjiagang,215600)
出处 《实用癌症杂志》 2020年第2期267-269,共3页 The Practical Journal of Cancer
关键词 乳腺癌 前哨淋巴结 转移 Breast cancer Sentinel lymph node Metastasis
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