摘要
目的分析阿替普酶静脉溶栓联合疏血通注射液治疗急性脑梗死的临床治疗效果。方法选取该院自2016年1月-2019年7月收治的急性脑梗死患者60例作为研究对象,所有患者均进行阿替普酶静脉溶栓治疗,随机分为观察组(30例)与对照组(30例)两组,对照组患者给予依达拉奉注射液治疗,观察组患者在对照组基础上给予疏血通注射液治疗,评价两组患者治疗前后的神经功能缺损情况和治疗效果。结果从神经功能缺损(NIHSS)评分看,治疗前,两组患者神经功能缺损(NIHSS)评分差异无统计学意义(t=2.31,P>0.05);治疗1、2周后,观察组患者神经功能缺损(NIHSS)评分明显低于对照组,组间差异有统计学意义(t=8.27、9.52,P<0.05)。从临床治疗效果看,观察组治愈、显著及有效的患者数量为28例,治疗有效率为93.3%,明显高于对照组(83.3%),差异有统计学意义(χ^2=5.13,P<0.05)。结论治疗急性脑梗死应用阿替普酶静脉溶栓联合疏血通注射液,安全性较高,对脑梗死患者的神经功能恢复具有重要作用,可有效改善患者的临床症状,具有良好的治疗效果,建议临床推广应用。
Objective To analyze the clinical therapeutic effect of alteplase combined with Shuxuetong injection in the treatment of acute cerebral infarction. Methods Sixty patients with acute cerebral infarction admitted to the hospital from January 2016 to July 2019 were enrolled. All patients underwent intravenous thrombolytic therapy with alteplase, and were randomly divided into observation group(30 cases) and the control group(30 cases), the control group was treated with edaravone injection, and the observation group was treated with Shuxuetong injection on the basis of the control group. The neurological deficits and treatments before and after treatment were evaluated. Results From the neurological deficit(NIHSS) score, there was no significant difference in neurological deficit(NIHSS) scores between the two groups before treatment,no statistically significant between the groups( t=2.31,P>0.05);after 2 weeks,the neurological deficit(NIHSS) score of the observation group was significantly lower than that of the control group, and there was significant statistical significance between the groups(t=8.27, 9.52, P<0.05). From the clinical treatment effect, the number of patients who were cured, significant and effective in the observation group was 28 cases, and the effective rate was 93.3%, which was significantly higher than that of the control group(83.3%),which was statistically significant(χ^2=5.13, P<0.05). Conclusion The treatment of acute cerebral infarction with alteplase intravenous thrombolysis combined with Shuxuetong injection is safe, and has an important role in the recovery of neurological function in patients with cerebral infarction. It can effectively improve the clinical symptoms of patients and has a good treatment. The effect is recommended for clinical application.
作者
赵娟
ZHAO Juan(Department of Neurology,Xuyi Hospital of Traditional Chinese Medicine,Xuyi,Jiangsu Province,211700 China)
出处
《世界复合医学》
2019年第12期183-185,共3页
World Journal of Complex Medicine
关键词
急性脑梗死
阿替普酶
疏血通注射液
临床治疗效果
Acute cerebral infarction
Alteplase
Shuxuetong injection
Clinical treatment effect
