摘要
目的:探讨阿托伐他汀治疗创伤性硬膜下积液(TSE)的疗效。方法:选取120例创伤性硬膜下积液患者随机分为观察组(n=57)和对照组(n=63)。对照组行常规保守治疗;观察组在此基础上加用口服阿托伐他汀进行治疗,根据患者病情改善程度确定治疗时间,所有病例中,积液完全吸收或者超过6个月无改善都将停止研究。结果:治疗后,观察组有效率明显高于对照组(P<0.01);治疗后观察组硬膜下积液量改善程度明显高于对照组(P<0.01),且治疗时间相比对照组明显缩短(P<0.01);观察组预后不良发生率低于对照组(P<0.01)。结论:口服阿托伐他汀对创伤性硬膜下积液的治疗有一定疗效。
Objective:To investigate the curative effect of atorvastatin on traumatic subdural effusion(TSE).Methods:120 patients with traumatic subdural effusion were randomly divided into the observation group(n=57)and the control group(n=63).The control group was asked to rest in bed and given routine conservative treatment.On this basis,the observation group was given oral atorvastatin.The treatment time was determined according to improvement degree of of patients’conditions.In all the cases,if effusion was completely absorbed or there was no improvement more than 6 months,the study would be stopped.Results:After treatment,response rate of observation group was significantly higher than that of control group(P<0.01).After treatment,improvement degree of TSE volume in observation group was significantly higher than that in control group(P<0.01),while treatment time was significantly shorter than that in control group(P<0.01).The incidence of poor prognosis in observation group was lower than that in control group(P<0.01).Conclusion:There is certain curative effect of oral atorvastatin on TSE.
作者
张永安
徐建平
陈旭
龚绍慧
余斌
熊成英
詹剑
ZHANG Yong-an;XU Jian-ping;CHEN Xu;GONG Shao-hui;YU Bin;XIONG Cheng-ying;ZHAN Jian(Shangrao People’s Hospital,Shangrao Jiangxi 334000,China)
出处
《药品评价》
CAS
2019年第22期12-13,共2页
Drug Evaluation
关键词
阿托伐他汀
创伤性硬膜下积液
非手术治疗
预后
Atorvastatin
Traumatic Subdural Effusion
Non-surgical Treatment
Prognosis
