摘要
目的:采用超声多普勒及全自动生化分析仪研究和探讨老年糖尿病患者血糖水平与颈动脉斑块的相关性。方法:以本院住院治疗的160例糖尿病患者为研究对象,按照患者是否存在颈动脉斑块分为无斑块组(19例)和有斑块组(141例),有斑块组患者中,按照斑块的等级不同分成Ⅰ级组、Ⅱ级组和Ⅲ级组。将160例患者再次按照糖化血红蛋白的控制情况分为控制良好组(糖化血红蛋白≤6.5%)和控制不良组(糖化血红蛋白>6.5%)。通过测定患者的颈动脉斑块、血糖、糖化血红蛋白等指标,比较分析患者血糖水平与颈动脉斑块的相关性。结果:有斑块组患者的糖化血红蛋白、空腹血糖和餐后2h血糖的指标明显高于无斑块组患者,有斑块组患者中,斑块Ⅱ级组和斑块Ⅲ级组的糖化血红蛋白、空腹血糖和餐后2h血糖的指标明显高于斑块Ⅰ级组;糖化血红蛋白控制良好组中,无斑块组患者18例,斑块Ⅰ级患者24例,斑块Ⅱ级患者8例,斑块Ⅲ级患者11例;糖化血红蛋白控制不良组中无斑块组患者1例,斑块Ⅰ级组患者2例;斑块Ⅱ级患者27例,斑块Ⅲ级患者69例,患者颈动脉斑块与糖化血红蛋白水平、空腹血糖和餐后2h血糖水平呈正相关。结论:老年糖尿病患者血糖水平、糖化血红蛋白水平与颈动脉斑块呈正比,颈动脉斑块的严重程度可以通过糖化血红蛋白水平进行调节。
Objective: To study the correlation between blood glucose level and carotid plaque in elderly patients with diabetes mellitus by ultrasonic Doppler and automatic biochemical analyzer. Methods: 160 diabetic patients in our hospital were divided into plaque free group(19 cases) and plaque group(141 cases) according to the presence of carotid plaque. The patients in plaque group were divided into gradeⅢ group, gradeⅢ group and gradeⅢ group according to the grade of plaque. According to the control of HbA1 c, 160 patients were divided into good control group(HbA1 c≤6.5%) and bad control group(HbA1 c >6.5%). By measuring the carotid plaque, blood glucose, glycosylated hemoglobin and other indicators, the correlation between blood glucose level and carotid plaque was analyzed. Results: The indexes of glycosylated hemoglobin, fasting blood glucose and 2-hour postprandial blood glucose in the patients with plaque were significantly higher than those in the patients without plaque. The indexes of glycosylated hemoglobin, fasting blood glucose and 2-hour postprandial blood glucose in the patients with plaque were significantly higher than those in the patients with plaque. In the patients with good control of glycosylated hemoglobin, 18 were in the patients without plaque and gradeⅢ plaque There were 24 patients, 8 patients with gradeⅢ plaque, 11 patients with gradeⅢ plaque, 1 patient without grade I plaque, 2 patients with gradeⅢ plaque, 27 patients with gradeⅢ plaque, 69 patients with gradeⅢ plaque, and the carotid plaque was positively correlated with the level of HbA1 c, fasting blood glucose and 2-hour postprandial blood glucose. Conclusion: The levels of blood glucose and glycosylated hemoglobin in elderly diabetic patients are in direct proportion to carotid plaque, and the severity of carotid plaque can be regulated by the level of glycosylated hemoglobin.
作者
边艳菊
BIAN Yan-ju(Shenyang First Peopleʼs Hospital,Liaoning Shenyang 110044)
出处
《中国医疗器械信息》
2020年第1期78-79,共2页
China Medical Device Information
关键词
糖尿病
颈动脉斑块
糖化血红蛋白
血糖水平
diabetes mellitus
carotid plaque
glycosylated hemoglobin
blood glucose level
