摘要
目的:分析对血管性痴呆患者给予多奈哌齐、匹伐他汀联合治疗的效果及预后。方法:将2017年9月~2018年9月接收的98例血管性痴呆患者按治疗方式的差异分为参照组、试验组,分别给予多奈哌齐单独治疗、匹伐他汀与多奈哌齐联合治疗,对比两组治疗效果。结果:试验组MMSE评分、QQLAD评分均高于参照组且ADL评分低于参照组(P<0.05);试验组低密度蛋白、三酰甘油、总胆固醇水平低于参照组且高密度蛋白水平高于参照组(P<0.05)。结论:多奈哌齐、匹伐他汀联合治疗能预防、延缓患者痴呆症状进展,促进患者认知、生活能力恢复。
Objective:To analyze the effect and prognosis of donepezil combined with pivastatin in the treatment of patients with vascular dementia.Methods:98cases of vascular dementia patients who were received in a hospital from September 2017to September 2018were selected and divided into the control group and the experimental group according the differences treatment patterns,separately treated with donepezil alone and pivastatin combined with donepezil,the therapeutic effects of the two groups were compared.Results:The MMSE score,QQLAD score in the experimental group were higher than the control group and ADL score was lower than the control group(P<0.05);The low density protein,triacylglycerol and total cholesterol levels in the experimental group were lower than the control group,and high density protein level were higher than the control group(P<0.05).Conclusion:Donepezil combined with pivastatin in the treatment of patients with vascular dementia can prevent and delay the development of dementia symptoms,promote the recovery of cognition and life ability of the patients.
作者
徐小皓
蔡晓娜
谢佳慧
Xu Xiaohao;Cai Xiaona;Xie Jiahui(Third Department of Neurology,Jiamusi Central Hospital,Jiamusi 154002;Department of Blood Transfusion,Jiamusi Central Hospital,Jiamusi 154002;Department of Thoracic Surgery,Jiamusi Central Hospital,Jiamusi 154002)
出处
《数理医药学杂志》
2020年第1期108-109,共2页
Journal of Mathematical Medicine
