摘要
目的分析对比中晚期宫颈癌患者采用全身静脉化疗与子宫动脉关注化疗的临床效果。方法选取2010年7月-2014年7月期间到我院接受治疗的中晚期宫颈癌患者100人作为研究分析对象,将其随机分为试验组和对照组,每组50人。对试验组的患者实施子宫动脉关注化疗,对照组患者采用全身静脉化疗。对2组患者治疗的化疗有效率、五年生存率、病理危险因素发生情况、不良反应发生率进行观察对比。结果试验组患者的化疗有效率(89%)明显高于试验组(50%),试验组患者病理因素出现率(23%)比对照组患者(75%)低,对照组患者五年生存率(62%)低于对照组(92%),试验组患者的不良反应发生率(23%)与对照组(76%)相比,明显降低。两组数据的差异具有统计学意义(P <0.05)。结论与全身静脉化疗手段相比,子宫动脉关注化疗手段对治疗中晚期宫颈癌能发挥安全有效的作用,提高化疗有效率和患者的五年生存率,降低不良反应发生率和病理危险因素,提升手术的操作容易程度。
Objective To analyze and compare the clinical effect of systemic intravenous chemotherapy and uterine artery focused chemotherapy in patients with advanced cervical cancer. Methods From July 2010 to July 2014, 100 patients with advanced cervical cancer who were treated in our hospital were randomly divided into experimental group and control group, 50 in each group. The patients in the experimental group were treated with uterine artery focused chemotherapy, while the patients in the control group were treated with systemic vein chemotherapy. The effective rate of chemotherapy, 5-year survival rate, incidence of pathological risk factors(including deep muscularis involvement, vascular cancer thrombus, periuterine infiltration rate and lymph node metastasis rate) and incidence of adverse reactions were observed and compared between the two groups. Results The effective rate of chemotherapy in the test group(89%) was significantly higher than that in the test group(50%), the incidence of pathological factors in the test group(23%) was lower than that in the control group(75%), the 5-year survival rate in the control group(62%) was lower than that in the control group(92%), and the incidence of adverse reactions in the test group(23%) was significantly lower than that in the control group(76%). The difference between the two groups of data was statistically significant(P < 0.05). Conclusion Compared with systemic intravenous chemotherapy, uterine artery focused chemotherapy can play a safe and effective role in the treatment of advanced cervical cancer, improve the effective rate of chemotherapy and the survival rate of patients, reduce the incidence of adverse reactions and pathological risk factors, and improve the ease of operation.
作者
宋超冉
SONG Chaoran(Department of Oncology,Hinggan League Peoples Hospital,Ulan Hot Inner Mongolia 137400,China)
出处
《中国卫生标准管理》
2020年第2期81-83,共3页
China Health Standard Management
关键词
中晚期
宫颈癌
全身静脉化疗
子宫动脉关注化疗
化疗方式
效果
对比分析
middle and advanced stage
cervical cancer
systemic intravenous chemotherapy
uterine artery focus chemotherapy
chemotherapy mode
effect
comparative analysis
