摘要
目的观察桂枝汤联合沙美特罗替卡松气雾剂治疗支气管哮喘的临床效果。方法选取2017年6月~2019年2月我院收治的80例支气管哮喘患者作为研究对象,将其随机分为对照组与观察组,每组各40例。对照组患者单采用沙美特罗替卡松气雾剂治疗,观察组患者在对照组治疗基础上加服桂枝汤,2剂/d,早晚各1次。比较两组患者的临床治疗效果、喘息症状消失时间、治疗前后肺功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC]水平及不良反应发生情况。结果观察组患者的治疗总有效率为95.00%,高于对照组的80.00%,差异有统计学意义(P<0.05)。观察组患者的喘息症状消失时间为(5.3±0.6)d,短于对照组的(7.6±0.7)d,差异有统计学意义(P<0.05)。治疗前,两组患者的肺功能指标(FEV1、FVC、FEV1/FVC)水平比较,差异无统计学意义(P>0.05);治疗后,观察组患者的肺功能指标(FEV1、FVC、FEV1/FVC)水平高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的肺功能指标(FEV1、FVC、FEV1/FVC)水平高于本组治疗前,差异有统计学意义(P<0.05)。对照组患者治疗期间发生4例(10.00%)不良反应,观察组患者发生2例(5.00%)不良反应,两组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。结论桂枝汤联合沙美特罗替卡松气雾剂治疗支气管哮喘的效果显著,能够缩短患者的喘息症状时间,改善患者的肺功能,不良反应少,值得临床应用与推广。
Objective To observe the clinical effect of Guizhi Decoction combined with Salmeteroticasone Aerosol in the treatment of bronchial asthma.Methods A total of 80 patients with bronchial asthma admitted to our hospital from June 2017 to February 2019 were selected as the subjects of this study.The patients were randomly divided into control group and observation group,with 40 cases in each group.The control group was treated with Salmeteroticasone Aerosol alone.On the basis of the treatment of the control group,patients in the observation group were given Guizhi Decoction,2 doses/d,once in the morning and once in the evening.The clinical treatment effect,the disappearance time of wheezing symptoms,levels of pulmonary function indexs(forced expiratory volume in 1 second[FEV1],forced vital capacity[FVC],FEV1/FVC)before and after treatment,and occurrence of adverse reactions in the two groups were compared.Results The total effective rate of the observation group was 95.00%,which was higher than that of the control group(80.00%),and the difference was statistically significant(P<0.05).The disappearance time of wheezing symptoms in the observation group was(5.3±0.6)d,which was shorter than that in the control group for(7.6±0.7)d,and the difference was statistically significant(P<0.05).Before treatment,the levels of pulmonary function indexs(FEV1,FVC,FEV1/FVC)were compared between the two groups,and the differences were not statistically significant(P>0.05).After treatment,the levels of pulmonary function indexs(FEV1,FVC,FEV1/FVC)in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of pulmonary function indexs(FEV1,FVC,FEV1/FVC)in the observation group were higher than those before treatment,and the differences were statistically significant(P<0.05).During the treatment period,4 cases(10.00%)of adverse reactions occurred during treatment in the control group and 2 cases(5.00%)in the observation group.There was no signi
作者
陈立胜
许爱婷
费春羡
CHEN Li-sheng;XU Ai-ting;FEI Chun-xian(Department of Geriatrics,Yangjiang People′s Hospital,Guangdong Province,Yangjiang 529500,China)
出处
《中国当代医药》
2020年第2期39-41,共3页
China Modern Medicine
基金
广东省阳江市科技计划项目(社发[2018]38)
关键词
桂枝汤
沙美特罗替卡松气雾剂
支气管哮喘
喘息
肺功能
不良反应
Guizhi Decoction
Salmeteroticasone Aerosol
Bronchial asthma
Wheeze
Pulmonary function
Adverse reactions
