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阿立哌唑合并氨磺必利治疗以阴性症状为主的精神分裂症疗效研究 被引量:4

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摘要 目的探究阿立哌唑合并氨磺必利治疗以阴性症状为主的精神分裂症疗效。方法选择近年我院收治的60例以阴性症状为主的精神分裂症患者,随机分为观察组和对照组各30例,对照组予以阿立哌唑治疗,观察组在此基础上联合氨磺必利治疗,两组连续治疗8周,对比两组治疗前后各时期阴性症状变化、临床疗效及用药安全性。结果观察组治疗第1、4、8周末的PANSS阴性评分均分别低于同期对照组(P<0.05)。观察组临床总有效率为73.3%,高于对照组的53.3%(P<0.05)。两组药物不良反应率分别为13.3%、10.0%(P>0.05)。结论阿立哌唑联合并氨磺必利治疗阴性症状为主的精神分裂症起效快,其临床疗效确切,且治疗安全性较高。
作者 胡雨
出处 《当代临床医刊》 2019年第6期515-516,共2页 Journal of Contemporary Clinical Medicine
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