摘要
目的:探讨B超引导神经内镜微创手术治疗高血压脑出血(HICH)的临床效果。方法:将笔者所在医院2017年1月-2019年5月收治的64例HICH患者按照随机数字表法分为两组,对照组32例予以开颅血肿清除术治疗,研究组32例予以B超引导神经内镜微创手术治疗。比较两组术前血肿量、术后血肿量、术中出血量、颅内压、格拉斯哥预后量表(GOS)评分、转化生长因子-β1(TGF-β1)、神经元特异性烯醇化酶(NSE)、降钙素原(PCT)、C反应蛋白(CRP)水平。结果:两组术前血肿量比较,差异无统计学意义(P>0.05);研究组术后血肿量及术中出血量均少于对照组,差异均有统计学意义(P<0.05);两组干预前GOS评分、颅内压、NSE、TGF-β1、CRP、PCT水平比较,差异均无统计学意义(P>0.05);干预后两组GOS评分、NSE、CRP、PCT水平均较干预前升高,颅内压、TGF-β1水平均较干预前降低,且研究组GOS评分、TGF-β1均高于对照组,颅内压、NSE、CRP、PCT水平均低于对照组,差异均有统计学意义(P<0.05)。结论:B超引导神经内镜微创手术治疗HICH效果确切,可显著降低颅内压,改善预后。
Objective:To investigate the clinical effect of B-mode ultrasonography-guided neuroendoscopic minimally invasive surgery in the treatment of hypertensive intracerebral hemorrhage(HICH).Method:A total of 64 patients with HICH admitted to our hospital from January 2017 to May 2019 were divided into two groups according to random number method.And 32 patients in the control group were treated by craniotomy hematoma removal,and 32 patients in the study group were treated by B-mode ultrasonography-guided neuroendoscopic minimally invasive surgery.The preoperative hematoma volume,postoperative hematoma volume,intraoperative hemorrhage volume,intracranial pressure,Glasgow prognosis scale(GOS),transforming growth factor-β1(TGF-β1),neuron-specific enolase(NSE),procalcitonin(PCT),and C-reactive protein(CRP)levels were compared between the two groups.Result:Preoperative hematoma volume were compared between the two groups,and the difference was not statistically significant(P>0.05).Postoperative hematoma volume and intraoperative hemorrhage volume in the study group were less than those of the control group,and the differences were statistically significant(P<0.05).GOS score,intracranial pressure,NSE,TGF-β1,CRP and PCT levels before intervention were compared between the two groups,and the differences were not statistically significant(P>0.05).After intervention,GOS score,levels of NSE,CRP and PCT of the two groups were higher than those before intervention,while intracranial pressure and the level of TGF-β1 were lower than those before intervention,and GOS score and the level of TGF-β1 in the study group were higher than those of the control group,and intracranial pressure,levels of NSE,CRP and PCT were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion:B-mode ultrasonography-guided neuroendoscopic minimally invasive surgery is effective in the treatment of HICH,which can significantly reduce intracranial pressure and improve prognosis.
作者
刘骞
LIU Qian(First Affiliated Hospital of Nanhua University,Hengyang 421000,China)
出处
《中外医学研究》
2019年第36期12-14,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
高血压脑出血
B
超引导神经内镜微创手术
开颅血肿清除术
神经元特异性烯醇化酶
Hypertensive intracerebral hemorrhage
B-mode ultrasonography-guided neuroendoscopic minimally invasive surgery
Craniotomy hematoma removal
Neuron-specific enolase
