摘要
目的探讨改良生肌玉红膏治疗老年带状疱疹患者的效果,以期为带状疱疹神经痛患者提供一种快速的止痛、促进创面早期愈合的方法。方法采用随机对照试验法,选择2017年1月至2019年3月本院就诊的60例老年带状疱疹患者,运用随机数字表法将患者随机分为试验组和对照组,每组各30例。对照组患者采用抗病毒、营养神经、必要时给予止痛药,局部皮损采用3%硼酸湿敷,试验组患者在药物治疗基础上采用改良生肌玉红膏涂抹局部创面,治疗时间10d。比较两组患者治疗前及治疗后1d、3d、5d、7d、10d各时间点视觉模拟评分法(visual analogue scale,VAS),匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)、疼痛缓解时间、止疱时间、结痂时间、脱痂时间等指标。结果两组患者治疗效果比较,P<0.001,差异具有统计学意义,试验组治疗效果优于对照组。两组患者治疗前与治疗后不同时间点疼痛评分重复测量资料方差分析结果显示:治疗时间与治疗方式间有交互作用(F=135.91,P<0.001,G-Gε=0.75),治疗后各时间点两组疼痛评分比较,差异具有统计学意义,均P<0.001,试验组患者疼痛评分低于对照组。两组患者治疗前与治疗后不同时间点睡眠质量评分重复测量资料方差分析结果显示:治疗时间与治疗方式间有交互作用(F=100.70,P<0.001,G-Gε=0.54),治疗后各时间点两组睡眠质量评分比较,差异具有统计学意义,均P<0.001,试验组睡眠质量评分低于对照组。两组患者疼痛缓解时间、止疱时间、结痂时间、脱痂时间比较,均P<0.001,差异具有统计学意义,试验组各项指标优于对照组。结论改良生肌玉红膏治疗老年带状疱疹的效果好,能有效改善老年带状疱疹患者的疼痛情况及睡眠质量,促进创面愈合,值得临床推广应用。
Objective To explore the therapeutic effect of modified Shengjiyuhong ointment on elderly patients with herpes zoster in order to provide a rapid analgesic and early wound healing method for them.Methods A total of 60 elderly patients with herpes zoster admitted to our hospital from January 2017 to March 2019 were selected and randomized equally into trial group and control group with the random number table method.The control group was treated with anti-virus,neurotrophic medication,and painkiller when necessary,along with application of 3%boric acid on local skin lesion.The trial group was managed with the modified Shengjiyu paste on skin lesions for 10 days besides the same treatment as in the control group.The two groups were compared in terms of pain relief time,blister stopping time,scabbing time,scab removal time as well as the results by visual analogue scale(VAS)1 days,5 days,7 days and 10 days after treatment and Pittsburgh sleep quality index(PSQI)before and after treatment.Results Compared with the control group,the clinical efficacy of the trial group was better(P<0.001).The results of Anova of pain scores at different time points before and after treatment showed that there was an interaction effect between treatment time and treatment method(J=135.91,P<0.001,g-g constant=0.75).The difference in pain scores between the two groups at different time points after treatment was statistically significant(P<0.001).The pain scores of the trial group were lower than those of the control group.Two groups of difierent time points before and after treatment in sleep quality score repeated measurement data analysis of variance results showed that there were interaction between treatment time and treatment(F=100.70,P<0.001,epsilon G-G=0.54),each time point in the two groups after treatment pain score comparison,and the difference was statistically significant(P<0.001).The score on patients sleep quality in the trial group was lower than that of the control group.There were significant differences between the gro
作者
许璧瑜
李敏宜
张玉玲
孙保国
Xu Biyu;Li Minyi;Zhang Yuling;Sun Baoguo(The First Affiliated Hospital,Sun Yat-sen,Guangzhou,510080,China)
出处
《现代临床护理》
2019年第10期34-40,共7页
Modern Clinical Nursing
关键词
带状疱疹
生肌玉红膏
改良
神经痛
老年人
随机对照试验法
herpes zoster
Shengjiyuhong ointment
improvement
neuralgia
the old patient
randomized control trial
