摘要
目的:探讨宝根1号方联合穴位敷贴治疗儿童哮喘缓解期的临床疗效。方法:纳入150例肺脾气虚证哮喘缓解期患儿,随机分为观察组75例和对照组75例。观察组患儿给予宝根1号方口服联合穴位敷贴治疗,对照组患儿给予穴位敷贴治疗,两组观察周期均为2个月。比较两组患儿的中医主症(咳嗽、喘息、气促、胸闷)评分、次症(易于感冒、纳差、汗多、面黄)评分;评价患儿的中文版儿童哮喘控制测试问卷(Ch-CACT)评分;检测患儿的免疫指标水平,包括免疫球蛋白(Ig)A、IgG、IgM、嗜酸性粒细胞(EOS)计数。结果:研究最终对144例患儿的数据进行统计分析,包括观察组71例和对照组73例。①临床疗效:治疗后,观察组和对照组患儿的临床总有效率分别为78.87%和61.64%,观察组的疗效优于对照组(P<0.05)。②主症评分:治疗后,两组患儿的咳嗽、喘息、气促、胸闷评分均下降(P<0.05),且观察组患儿的各项主症评分低于对照组(P<0.05)。③次症评分:治疗后,观察组患儿的易于感冒、纳差、汗多、面黄评分较治疗前均降低(P<0.05),对照组患儿仅易于感冒评分降低(P<0.05),且观察组患儿的纳差、汗多、面黄评分低于对照组(P<0.05)。④Ch-CACT评分:治疗后,两组患儿的Ch-CACT评分均显著升高(P<0.05),但组间比较差异无统计学意义(P>0.05)。⑤免疫指标:治疗后,两组患儿的IgA、IgG、IgM水平均升高(P<0.05),EOS计数水平降低(P<0.05),且观察组患儿的IgA、IgG水平高于对照组(P<0.05),EOS计数水平低于对照组(P<0.05)。结论:宝根1号方联合穴位敷贴能更好地改善哮喘缓解期患儿的临床症状和免疫功能,可在临床推广。
Objective: To explore the clinical efficacy of Baogen-Ⅰ Decoction combined with acupoint application in treating children with asthma at remission stage. Methods: One hundred and fifty asthma children at remission stage with syndrome of lung and spleen qi-deficiency were included and randomly divided into the observation group(75 cases) and control group(75 cases). The children in the observation group were orally treated with Baogen-Ⅰ Decoction combined with acupoint application, and the children in the control group were treated with acupoint application. The observation course was 2 months. The scores of Chinese medical main symptoms(including cough, wheezing, short breath and chest distress) and secondary symptoms(including susceptible to cold, anorexia, hyperhidrosis and yellowish complexion) were compared between the two groups. The score of Chinese-childhood asthma control test(Ch-CACT) was evaluated. The levels of immune function indexes including IgA, IgG, IgM and eosinophilia(EOS) count were detected. Results: Finally the data of 144 children were analyzed, including 71 cases in the observation group and 73 cases in the control group.(1)Clinical efficacy: After treatment,the clinical total effective rates of the observation group and the control group were 78.87% and61.64% respectively,and the efficacy of the observation group was better than that of the control group( P<0.05).(2)Scores of the main symptoms: After treatment,the scores of cough,wheezing,short breath and chest distress were decreased in both groups( P<0.05),and the scores of all items of main symptoms in the observation group were lower than those in the control group( P<0.05).(3)Scores of the secondary symptoms: After treatment,the scores of susceptible to cold,anorexia,hyperhidrosis and yellowish complexion in the observation group were decreased( P<0.05),the score of susceptible to cold in the control group was also decreased( P<0.05),and the scores of anorexia,hyperhidrosis and yellowish complexion in the observation group were lo
作者
陆容
丁惠玲
叶智祺
景晓平
LU Rong;DING Huiling;YE Zhiqi;JING Xiaoping(Shanghai Children's Hospital,Children's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200040,China)
出处
《上海中医药大学学报》
CAS
2019年第6期33-37,共5页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
上海市卫计委中医药科研专项基金项目(2016LP025)
上海市科委中医类引导项目(19401931900,18401902500)
上海市进一步加快中医药事业发展三年行动计划项目[ZY(2018-2020)-FWTX-3025]
关键词
哮喘
缓解期
宝根1号方
穴位敷贴
儿童
asthma
remission stage
Baogen-Ⅰ Decoction
acupoint application
child
