摘要
空肠弯曲杆菌是一种重要的人兽共患病原菌,其引起的弯曲杆菌病是最常见的食源性细菌感染之一,可导致多种临床症状,包括腹泻、发烧、呕吐以及血便等。空肠弯曲杆菌主要通过黏附、定植、侵袭、产毒素等方式对宿主造成致病性,是多个毒力因子共同参与的结果。文章详细介绍了空肠弯曲杆菌致病性相关的毒力因子及其致病机制,为空肠弯曲杆菌病的诊断与防治和相关疫苗研制提供科学参考。
Campylobacter jejuni is an important zoonotic pathogen,and the campylobacteriosis caused by C.jejuni is one of the most common foodbome bacterial infections,which can lead to a variety of clinical symptoms,including diarrhea,fever,vomiting and bloody stools.The diseases of the host caused by C.jejuni are through the way of adhesion,colonization,invasion,toxin production,etc.Multiple virulence factors are involved in the process of pathopoiesis.In this review,the virulence factors related to the pathogenicity of C.jejuni and its function in the pathogenesis were introduced detailedly,which provided a scientific reference for the diagnosis and prevention of C.jejuni,and the development of vaccines.
作者
黄亚奇
熊静禹
沈达
林征宇
成大荣
HUANG Yaqi;XIONG Jingyu;SHEN Da;LIN Zhengyu;CHENG Darong(College of Veterinary Medicine,Yangzhou University,Yangzhou,Jiangsu 225009;Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses,Yangzhou,Jiangsu 225009)
出处
《中国家禽》
北大核心
2019年第22期46-51,共6页
China Poultry
基金
江苏现代农业(肉羊)产业技术体系疾病防控创新团队项目(JATS[2019]452)
扬州大学研究生培养创新工程项目(XKYCX18_109)
江苏省农业自主创新资金项目(CX(18)104)
江苏高校优势学科建设工程资助项目
关键词
空肠弯曲杆菌
毒力因子
致病机制
防控
Campylobacter jejuni
virulence factor
pathogenesis mechanism
control
