摘要
热射病是热损伤疾病中最严重的类型,由此导致的多器官功能障碍综合征(MODS)是热射病患者的重要死因.心血管系统是热损害的重要靶点之一,有研究表明,热应激可以导致心肌抑制、心脏传导异常及血流再分布,改变机体血流动力学状态,使热射病患者心电图、心脏超声、心肌损伤生物学标志物及血流动力学指标明显异常.本文就热射病心肌损害的病理生理学改变、心肌结构改变及临床表现进行综述,以期为进一步认识热射病心肌损害及开展后续研究提供参考.
Heat stroke is the most serious type of heat-related diseases,and the induced multiple organ dysfunction syndrome(MODS)is an important cause of death for heat stroke patients.The cardiovascular system is one of the important targets of heat injury.Studies have reported that heat stress can lead to myocardial inhibition,abnormal heart conduction and blood flow redistribution,thus changing the hemodynamic state,leading to obvious abnormalities in electrocardiogram,echocardiography,myocardial injury biological markers and hemodynamic indicators of patients with heat stroke.In this article,the pathophysiological and histological changes and clinical manifestations of heatstroke-induced myocardial injury are reviewed,aiming to provide references for further understanding and research of myocardial damage caused by hyperthermia.
作者
娄云鹏
林慧艳
王洪萍
陈玮
武玉田
李海玲
Lou Yunpeng;Lin Huiyan;Wang Hongping;Chen Wei;Wu Yutian;Li Hailing(Department of Intensive Care Unit,No.971 Hospital of Chinese People's Liberation Army Navy,Qingdao 266071,Shandong,China;Department of Intensive Care Unit,the Affiliated Hospital of Qingdao University,Qingdao 266000,Shandong,China)
出处
《中华危重病急救医学》
CAS
CSCD
北大核心
2019年第10期1304-1306,共3页
Chinese Critical Care Medicine
基金
济南军区后勤部科研计划重点项目(CJN15J011)。
关键词
热射病
心肌损害
病理生理学
组织学
临床表现
Heatstroke
Myocardial injury
Pathophysiology
Histology
Clinical feature
