摘要
热射病（HS）是以核心温度超过40？℃伴有中枢神经系统功能障碍（包括谵妄、抽搐、昏迷）为特点的严重威胁生命的疾病。高热和继发激活的全身炎症反应综合征（SIRS）是组织损伤继而导致多器官功能障碍综合征（MODS）的病理生理机制，是导致HS患者死亡的主要原因。HS所致的各器官损害各具特点，了解HS发病机制、各器官损害特点及变化规律，对该病的临床救治、研究和降低病死率具有重要意义。
Heat stroke （HS） is a life-threatening illness characterized by core body temperatures above 40？℃ coupled with central nervous system （CNS） dysfunction, including delirium, convulsions, and/or coma. Its morbidity has increased dramatically in the past few decades. Multiple organ dysfunction syndrome （MODS） is not only the most serious complication of HS, but also the leading cause of deaths. Understanding the pathogenesis, characteristic and advancement pattern of MODS caused by HS will have a profound effect on the clinical treatment, research and mortality decrease. The pathogenesis, injury characteristic of each system and organ, and treatment methods were summarized in this review so as to deepen the clinical recognition of this disease.
出处
《中华危重病急救医学》
CAS
CSCD
北大核心
2017年第2期188-192,共5页
Chinese Critical Care Medicine
基金
国家自然科学基金（81671966）
关键词
热射病
多器官功能障碍综合征
发病机制
治疗方法
Heat stroke
Multiple organ dysfunction syndrome
Pathogenesis
Treatment methods
