摘要
目的:分析血清肌酸激酶(CK)值作为劳力性热射病患者预后判别指标的意义。方法:回顾分析1995年9月-2007年8月6所部队医院的11例EHS病例。以预后为标准,将11例患者分为两组,死亡组(n=4)及存活组(n=7),比较两组病例入院后0 h、12 h、24 h、36 h、48 h、60 h、72 h的CK数值,并描绘48 h CK值的ROC曲线,分析CK值在发病早期判别预后的意义。结果:在入院后各时间点死亡组CK值持续升高,存活组CK值略升高后保持稳定并逐渐下降,两组CK值在48 h、60 h、72 h有显著差异(P<0.05),48 h CK值的ROC曲线AUC(area under the Roc curve)为0.893。结论:死亡患者与存活患者CK值的变化趋势显著不同,CK值可以在发病早期(48 h)判别预后。
Objective： To analyze the accuracy of CK value as a prognostic indicator in exertional heat stroke（EHS） patients.Methods： We retrospectively analyzed 11 cases of EHS in 6 military hospitals from Sep 1995 to Aug 2007.In terms of prognosis,the 11 patients were divided into two groups： D group（those who died,n=4）and S group（those who survived and were discharged,n=7）.We compared CK values in two groups at 0 h、 12 h、 24 h、 36 h、 48 h、 60 h、 72 h after admission and plotted the receiver-operating characteristic plots（ROC） curve at 48 hour to analyze the accuracy of CK value as a prognostic indicator in the initial stage of EHS.Results： The CK values continued to increase in D group at all time intervals after admission,the CK values were stable and generally decreased after a mild increase,the values between the two groups had significant deviation at 48 h、 60 h、 72 h after admission（P〈0.05）.CK ROC had an AUC of 0.893 at 48 h.Conclusion： The trends of CK in dead patients and survival patients are significantly different,the former is significantly higher than that of the latter.CK can be a useful indicator of the prognosis of EHS in the initial stage of EHS（48 h）.
出处
《军医进修学院学报》
CAS
北大核心
2008年第6期457-459,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
热射病
劳力性
肌酸激酶
死亡率
heat stroke,exertional heat stroke（EHS）
CK
motality
