摘要
脂肪酸结合蛋白7(FABP7)是脂肪酸结合蛋白(FABPs)家族成员之一,FABP7基因对大脑发育及中枢神经系统的调节至关重要。同时,FABP7位于脂质代谢的经典通路PPAR通路中,在脂质代谢、基因调控、细胞生长和分化过程中发挥重要的作用。目前,关于FABP7基因的研究主要集中于大脑发育及中枢神经系统的调节,对于家畜脂质代谢分子机制方面的研究相对较少。本文对FABP7的结构、分布及其在脂质代谢、神经系统和癌细胞增殖相关研究进展进行阐述,为今后利用FABP7基因相关育种研究提供参考。
Fatty acid binding protein 7(FABP7)is a member of the fatty acid binding proteins(FABPs)family.The FABP7 gene is critical for brain development and regulation of the central nervous system.Meanwhile,FABP7 is located in the classic PPAR pathway of lipid metabolism and plays an important role in lipid metabolism,gene regulation,cell growth and differentiation.At present,the research on FABP7 gene mainly focuses on the regulation of brain development and central nervous system,and there are relatively few studies on the molecular mechanism of lipid metabolism in domestic animals.In this review,the structure and distribution of FABP7 and its related research progress in lipid metabolism,nervous system and cancer cell proliferation were described,providing reference for future studies on FABP7 gene related breeding.
作者
吕阳
曹阳
高一
刘理想
薛佳佳
张国梁
LV Yang;CAO Yang;GAO YI;LIU Lixiang;XUE Jiajia;ZHANG Guoliang(College of Animal Sciences and Technology,Jilin Agricultural University,Jilin Changchun 130118,China;Branch of Animal Husbandry,Jilin Academy of Agricultural Sciences,Jilin Gongzhuling 136100,China)
出处
《中国畜牧杂志》
CAS
北大核心
2019年第12期43-46,共4页
Chinese Journal of Animal Science
基金
国家肉牛牦牛产业技术体系公主岭综合试验站(CARS-37)
国家重点研发计划项目(2018YFD0501802)
吉林省农业科技创新工程研究生基金项目
肉用草原红牛培育：畜禽品种培育项目
