摘要
目的探究分析同型半胱氨酸、胱抑素C、超敏C反应蛋白和纤维蛋白原与急性脑梗死患者的关系.方法选择2018年4月至2019年4月在本院进行治疗的急性脑梗死患者41例,作为研究组,选择同期体检健康者41例,作为常规组.检测两组的同型半胱氨酸、胱抑素C、超敏C反应蛋白和纤维蛋白原,分析相关指标与急性脑梗死之间的关系.结果常规组患者的同型半胱氨酸、胱抑素C、超敏C反应蛋白、纤维蛋白原水平较研究组更低,差异具有统计学意义(P<0.05).研究组的同型半胱氨酸与胱抑素C、超敏C反应蛋白间存在正相关关系,超敏C反应蛋白与纤维蛋白原、胱抑素C间存在正相关关系(P<0.05).同型半胱氨酸与纤维蛋白原间无相关性关系.4项指标联合测定的阳性率明显高于单独测定阳性率,差异具有统计学意义(P<0.05).结论同型半胱氨酸、胱抑素C、超敏C反应蛋白、纤维蛋白原与急性脑梗死的发生存在较为密切的联系,通过对相关指标的检测,能为临床诊断提供可靠依据,缓解患者的病情,有效改善预后恢复情况,值得临床推广.
Objective To investigate the relationship between homocysteine, cystatin C, hypersensitive C-reactive protein and fibrinogen in pa- tients with acute cerebral infarction. Methods 41 patients with acute cerebral infarction who were treated in our hospital from April 2018 to April 2019 were enrolled in the study group. 41 people with healthy physical examination were enrolled in the routine group. The two groups of homocys- teine, cystatin C, high-sensitivity C-reactive protein and fibrinogen were detected, and the relationship between the relevant indicators and acute cere- bral infarction was analyzed. Results The levels of homocysteine, cystatin C, hypersensitive C-reactive protein and fibrinogen in the conventional group were lower than those in the study group, and the difference was statistically significant (P<0.05). There was a positive correlation between homocysteine and cystatin C and high-sensitivity C-reactive protein in the study group. There was a positive correlation between high-sensitivity C- reactive protein and fibrinogen and cystatin C (P<0.05). There was no correlation between homocysteine and fibrinogen. The positive rate of the combined determination of the four indicators was significantly higher than that of the single determination, and the difference was statistically signif- icant (P<0.05). Conclusion The homocysteine, cystatin C, hypersensitive C-reactive protein and fibrinogen are closely related to the occurrence of acute cerebral infarction. By detecting the relevant indicators, it can provide a reliable basis for clinical diagnosis. The condition is relieved, and the prognosis recovery is effectively improved, which is worthy of clinical promotion.
作者
马爱金
Ma Aijin(Department of Neurology,Wujin People's Hospital,Jiangsu University,Changzhou,Jiangsu,213162,China)
出处
《当代医学》
2019年第35期65-67,共3页
Contemporary Medicine
