摘要
目的对临床发生输血不良反应的患者进行分析统计,为减少不良反应的发生和确保输血安全提供依据。方法收集昆明医科大学第一附属医院2014年1月至2017年1月发生的输血不良反应218例,对输血反应的类型及不同血液制品发生不良反应的情况进行统计分析。结果15035例输血患者共输血97248袋,其中218例发生输血不良反应,发生率为0.23%,其中输注红细胞类制品、血浆类制品、血小板、冷沉淀不良反应发生例数分别为95例(0.24%)、70例(0.18%)、48例(0.69%)、5例(0.04%),过敏反应145例(66.5%),发热反应55例(25.2%),其他反应18例(8.3%)。输血不良反应发生率最高的前3个科室是儿科、产科、肿瘤科。结论临床输血不良反应主要的影响因素是输血品种、次数等,有输血史的患者不良反应较高。严格把握输血指征,正确选择血液制品以及加强输血相关环节的监管,是降低输血不良反应发生率,保证输血安全的关键所在.
Objective To analysis the statistics of patients with adverse reactions to blood transfusion in clinical practice,in order to reduce the incidence of adverse reactions and provide a theoretic support for ensuring blood transfusion safety.Me thods 18 cases of adverse reactions to blood transfusion in the First Affiliated Hospital of Kunming Medical University from January 2014 to January 2017 were collected.The blood transfusion reaction types and adverse reactions of blood products were statistically analyzed.Re s ults In the 15035 cases transfusion cases,transfusion adverse reactions occurred in 218 cases,with a occurrance rate of 0.23%.The cases caused by the injection of red blood cell transfusion products,plasma products,platelet and by cryopecipitate adverse reaction were respectively 95 cases(0.24%),and 70 cases(0.18%),48 cases(0.69%)and 5 cases(0.04%).Meanwhile allergic reaction occurred in 145 cases(66.5%),fever reaction in 55 cases(25.2%)and other reaction in 18 cases(8.3%)in the total 218 cases.The top three departments with the highest incidence of adverse reactions to blood transfusion were pediatrics,obstetrics and oncology.Conclus ion The clinical incidence of adverse transfusion reactions is influenced by many factors,among which the varieties transfused and the number of blood transfusion are the main influence factors.Patients with a history of transfusion have a higher rate of adverse reactions.Thus a strict follow of the transfusion indications,correct selection of blood components,as well as careful monitoring and managing of the steps in blood transfusion are the keys to the decrease in the incidence of adverse transfusion reactions and ensurance of the blood transfusion safety.
作者
李德应
王玉明
柴华香
董伟群
LI De-ying;WANG Yu-ming;CHAI Hua-xiang;DONG Wei-qun(Dept.of Blood Transfusion,The 1st Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650032;Dept.of Clinical Laboratory,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101,China)
出处
《昆明医科大学学报》
CAS
2019年第11期59-62,共4页
Journal of Kunming Medical University
基金
云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2018FE001)
关键词
输血
不良反应
回顾分析
预防
Blood transfusion
Adverse transfusion reactions
Retrospective analysis
Precaution
