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慢性乙型肝炎与肝硬化患者血清乙型肝炎表面抗原及乙型肝炎病毒DNA载量水平比较 被引量:3

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摘要 目的比较慢性乙型肝炎与肝硬化患者血清的乙型肝炎表面抗原(HBsAg)及乙型肝炎病毒(HBV)DNA载量水平,探讨其与慢性乙型肝炎及肝硬化的关系。方法选取2016年4月至2018年10月本院收治的经临床确诊的184例慢性乙型肝炎及肝炎后肝硬化的患者,根据临床诊断结果分为慢性乙型肝炎组和肝硬化组,各92例。所有患者均进行HBV DNA定量检测及乙型肝炎5项定量检测,对比2组患者血清HBsAg和HBV DNA载量水平及其相关性。结果慢性乙型肝炎组患者的HBsAg及HBV DNA载量水平均较乙型肝炎肝硬化组患者高,差异有统计学意义(P<0.05);HBsAg及HBV DNA载量水平在慢性乙型肝炎组及乙型肝炎肝硬化组中呈正相关。结论血清HBsAg及HBV DNA载量水平可有效反映慢性乙型肝炎及肝硬化患者的情况,且HBsAg与HBV DNA载量水平之间存在正相关。
作者 白娜
出处 《实用医技杂志》 2019年第10期1269-1270,共2页 Journal of Practical Medical Techniques
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  • 1CABELLO-VERRUGIO C, MORALES M G, CABRERA D ,et al. Angiotensin II receptor type 1 blockade decrea- ses CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles [ Jl. J Cell Mol Med, 2012,16(4) :752. 被引量:1
  • 2ZHOU S, QU X, YU Z, et al. Survivin as a potential early marker in the carcinogenesis of oral submucous fibrosis [ J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2010,109(4) :575. 被引量:1
  • 3OUZAN D,PENARANDA G,JOLY H,et al. Add-on peg- interferon leads to loss of HBsAg in patients with HBeAg- negative chronic hepatitis and HBV DNA fully sup- pressed by long-term nucleotide analogs [ J 1. J Clin Vir- ol,2013,58(4) :713. 被引量:1
  • 4ARAUZ J, MORENO M G, CORTES-REYNOSA P,et al. Coffee attenuates fibrosis by decreasing the expression of TGF-beta and CTGF in a murine model of liver damage [ J 1. J Appl Toxicol, 2013,33 ( 9 ) : 970. 被引量:1
  • 5LARSSON S B, EILARD A, MALMSTROM S,et al. HBsAg quantification for identification of liver disease in chronic hepatitis B virus carriers[ J3. Liver Int,2013,15(4) :409. 被引量:1
  • 6CHITYMITYRAPAP S, CHIEOCHANSIN T, CHAITEER- AKIJ R,et al. Prevalence of aflatoxin induced p53 muta- tion at codon 249 (R249s) in hepatocellular cm'cinoma patients with and without hepatitis B surface antigen ( HB- sag) [J]. Asian Pac J Cancer Prey,2013,14(12) :7675. 被引量:1
  • 7LEE S W,WON J Y ,KIM W J ,et al. Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis [ J ]. Mol Ther, 2013,21 (9) : 1767. 被引量:1
  • 8HONG M Z,HUANG W Q,MIN F,et al. Enhanced HB- sag synthesis correlates with increased severity of fibrosis in chronic hepatitis B patients [ J ]. PLoS One, 2014,9 ( 1 ) :e87344. 被引量:1
  • 9FATEEN A A, SHAHIN R Y, FARRES M N,et al. As- sessment of hepatic fibrosis and necroinflammation a- mong inactive HBsAg carriers in Egypt [ J]. Ann Hepa- tol,2012,11 (4) :464. 被引量:1
  • 10SHOUVAL D. Focus:quantitative HBsAg measurement as a new surrogate marker for assessment of hepatic fi- brosis in HBeAg+ chronic hepatitis B[J]. J Hepatol, 2013,58(6) : 1063. 被引量:1

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