摘要
目的进一步认识普通IFNα-2b治疗慢性乙型肝炎患者外周血中性粒细胞和血小板的变化规律。方法接受普通IFNα-2b治疗的24例CHB病人,观察48周。结果干扰素治疗后中性粒细胞数减少在第2周最明显,血小板减少在第4周内最明显,以后均逐渐恢复。结论干扰素所致外周血中性粒细胞和血小板数减少是可逆性的。
Objective To investigate the changes of blood neutrophils and platelets in patients with chronic hepatitis B during the use of ordinary IFN-α-2b treatment.Method 24 patients with chronic hepatitis B receiving ordinary IFN-α-2b treatment were followed-up for 48 weeks.Result After the use of IFN-α-2b,the obvious decrease of neutrophil and platelet counts appeared in the second week and fourth week,respectively,and both of them recovered gradually thereafter.Conclusion The decrease of neutrophils and platelets in blood during the use of ordinary IFN-α-2b is reversible and the outcome is good.
出处
《实用肝脏病杂志》
CAS
2011年第6期410-411,414,共3页
Journal of Practical Hepatology
关键词
慢性乙型肝炎
干扰素
中性粒细胞
血小板
Hepatitis B
Interferon-α-2b
Adverse effect
Neutrophils
Platelets
