摘要
目的:观察督灸联合西药治疗强直性脊柱炎(AS)肾虚督亏证的临床疗效。方法:将70例AS肾虚督亏证患者随机分为对照组和观察组各35例。2组患者均口服沙利度胺片、艾瑞昔布片治疗,观察组加予督灸。2组均连续治疗3个月。治疗前后评定脊柱疼痛视觉模拟评分法(VAS)评分、巴氏强直性脊柱炎功能指数(BASFI)、炎症病情活动指数(BASDAI)、"4"字试验评分、医师对患者病情的总体评分(PhGV评分)和肾虚督亏证评分,评测指地距、胸廓活动度、腰椎活动度、枕墙距。评价2组的疗效。结果:治疗后,观察组ASAS20达标率为100%,ASAS50达标率60.00%,BASDAI50达标率为54.29%,均分别高于对照组的80.00%、34.29%和28.57%,差异均有统计学意义(P<0.05)。观察组VAS评分、BASFI、BASDAI、肾虚督亏证评分、"4"字试验评分和PhGV评分均低于对照组(P<0.05),腰椎活动度和胸廓活动度均优于对照组(P<0.05),枕墙距和指地距均小于对照组(P<0.05)。结论:督灸联合西药治疗AS能进一步减轻疼痛等症状,有效控制疾病的活动,提高患者的运动活动能力,临床疗效优于单纯以西药治疗。
Objective:To observe the clinical effect of Du-moxibustion combined with western medicine for ankylosing spondylitis(AS).Methods:Divided 70 cases of patients with AS and kidney and Du-meridian deficiency syndrome into the control group and the observation group randomly,35 cases in each group.Both groups received the oral administration of thalidomide tablets and imrecoxib tablets,while the observation group additionally received Du-moxibustion.The treatment of both groups lasted for 3 months continuously.Before and after treatment,assessed the scores of visual analogue scale(VAS)for spinal pain,Bath ankylosing spondylitis functional index(BASFI),Bath ankylosing spondylitis disease activity index(BASDAI),scores of Patrick test,scores of physician’s global visual analogue scale(PhGV) and scores of kidney and Du-meridian deficiency syndrome,measured the finger-to-floor distance,thoracic mobility,lumbar mobility and the occiput-to-wall distance,and evaluated the clinical effect in both groups.Results:After treatment,the standard-reaching rate for ASAS20 was 100% in the observation group,being higher than 80.00% in the control group;the standard-reaching rate for ASAS50 was 60.00% in the observation group,being higher than 34.29% in the control group;the standard-reaching rate for BASDAI50 was 54.29% in the observation group,being higher than 28.57% in the control group,differences being significant(P<0.05).The scores of VAS,BASFI,BASDAI,scores of kidney and Du-meridian deficiency syndrome,scores of Patrick test and scores of PhGV in the observation group were all lower than those in the control group(P<0.05);the lumbar mobility and thoracic mobility were better than those in the control group(P<0.05);the occiput-to-wall distance and the finger-to-floor distance were shorter than those in the control group(P<0.05).Conclusion:Du-moxibustion combined with western medicine for AS can further relieve such symptoms as pain,effectively control the progression of disease and promote the exercise capacity and activity abil
作者
张晟
李小玉
郭乃亮
王伟
ZHANG Sheng;LI Xiaoyu;GUO Nailiang;WANG Wei
出处
《新中医》
CAS
2019年第11期223-226,共4页
New Chinese Medicine
关键词
强直性脊柱炎(AS)
肾虚督亏证
中西医结合疗法
督灸
沙利度胺
Ankylosing spondylitis(AS)
Kidney and Du-meridian deficiency syndrome
Integrated Chinese and western medicine therapy
Du-moxibustion
Thalidomide
