摘要
目的研究老年缺血性脑血管病患者实施神经节苷脂治疗的疗效。方法选择74例本院2017年10月至2018年10月收治的缺血性脑血管病患者,采用抽签法将其分为实验组与参照组,每组37例。其中参照组采用常规缺血性脑血管病治疗,实验组行神经节苷脂治疗,对比两组患者治疗前后血脂指标,治疗前后NDS、PAL评分,临床疗效。结果治疗前,两组患者血脂指标、PAL、NDS评分比较差异无统计学意义,治疗后实验组PAL、NDS评分均低于参照组,与参照组相比,治疗后实验组三酰甘油、胆固醇、低密度脂蛋白较低(P<0.05),实验组高密度脂蛋白水平高于参照组(P<0.05);实验组缺血性脑血管病临床疗效(94.59%)高于参照组(75.68%),组间差异具有统计学意义(P<0.05)。结论老年缺血性脑血管病患者行神经节苷脂治疗效果显著,能够有效改善患者临床症状,降低其PAL、NDS评分,应予以临床推广。
Objective To study the efficacy of ganglioside therapy in elderly patients with ischemic cerebrovascular disease.Methods Seventyfour patients with ischemic cerebrovascular disease were enrolled in our hospital.The enrollment time was from October 2017 to October 2018.They were divided into experimental group and reference group by drawing method,with 37 cases in each group.The reference group was treated with conventional ischemic cerebrovascular disease,and the experimental group was treated with ganglioside.The clinical efficacy of NDS and PAL scores before and after treatment of blood lipids in the two groups was compared.Results There were no differences in serum lipid index,PAL and NDS scores between the two groups before treatment.After treatment,the PAL and NDS scores of the experimental group were lower than the reference group(P<0.05).Compared with the reference group,the experimental group was treated with triacylglycerol.Cholesterol and low-density lipoprotein were lower.The high-density lipoprotein level in the experimental group was higher than that in the reference group.The clinical efficacy(94.59%)of the ischemic cerebrovascular disease in the experimental group was higher than that in the reference group(75.68%),the difference was statistically significant(P<0.05).Conclusion The treatment of ganglioside in elderly patients with ischemic cerebrovascular disease is effective,which can effectively improve the clinical symptoms of patients and reduce their PAL and NDS scores.It should be clinically promoted.
作者
杨琳
Yang Lin(Department of Neurology,Fushun Central Hospital,Fushun,Liaoning,113006,China)
出处
《当代医学》
2019年第32期48-50,共3页
Contemporary Medicine
