摘要
目的探讨奥曲肽治疗肝硬化合并上消化道出血的临床效果。方法选取2017年3月至2018年2月我院收治的84例肝硬化合并上消化道出血患者作为研究对象,随机将其分为甲组和乙组,各42例。甲组给予奥美拉唑治疗,乙组给予奥曲肽治疗,比较两组患者的治疗效果。结果乙组患者的治疗总有效率为95.24%,显著高于甲组的71.43%(P<0.05)。乙组患者的不良反应总发生率为4.76%,显著低于甲组的23.81%(P<0.05)。乙组患者的止血时间、症状缓解时间均短于甲组(P<0.05)。结论奥曲肽治疗肝硬化合并上消化道出血能提高患者的治疗效果,缩短治疗时间,值得临床应用和推广。
Objective To explore the clinical effect of octreotide in the treatment of cirrhosis with upper gastrointestinal bleeding.Methods A total of 84 patients with cirrhosis with upper gastrointestinal bleeding admitted in our hospital from March 2017 to February 2018 were selected as research objects and randomly divided into group A and group B,with 42 cases in each group.The group A was treated with omeprazole,and the group B was treated with octreotide.The treatment effects were compared between the two groups.Results The total effective rate of treatment in the group B was 95.24%,which was significantly higher than 71.43%in the group A(P<0.05).The total incidence of adverse reactions in the group B was 4.76%,which was significantly lower than 23.81%in the group A(P<0.05).The time of hemostasis and remission of symptoms in the group B were shorten than those in the group A(P<0.05).Conclusion Octreotide in the treatment of cirrhosis with upper gastrointestinal bleeding can improve the treatment effect of patients and shorten the treatment time,which is worthy of clinical application and promotion.
作者
邱丽美
QIU Li-mei(General Hospital of Panjiang Investment Holding Group Co.,Ltd.,Panzhou 553536,China)
出处
《临床医学研究与实践》
2019年第30期54-55,共2页
Clinical Research and Practice
关键词
奥曲肽
肝硬化
上消化道出血
octreotide
cirrhosis
upper gastrointestinal bleeding
