摘要
探讨空腹血糖受损(IFG)的社区老年人未来3年发展为糖尿病的危险因素。选取天津滨海新区老年IFG患者328例作为研究对象,所有受试者均参加身体活动能力测试、血液检查、人体测量学检查等客观检查,并完成问卷调查。在3年后,受试者重新进行1次内容相同的客观检查及问卷调查。在基线和3年的结果之间,基线数据中56例IFG患者进展为糖尿病。经多因素调整后,发现空腹血糖水平越高(OR=9.30,95%CI 2.84~30.48, P<0.01),握力/体重水平越低(OR=0.88,95%CI 0.82~0.94, P<0.01),其糖尿病发病率越高。此外,相比于单纯的高空腹血糖或低握力/体重者,高空腹血糖同时伴有低握力/体重者更易发展为糖尿病(P<0.05)。空腹血糖偏高和肌肉力量偏低与IFG患者3年后血糖恶化有关。本研究表明,除了血糖水平,身体活动能力也是老年人罹患糖尿病的危险因素。
To examine the risk factors for developing diabetes on its 3-year outcome in an elderly population with impaired fasting glucose (IFG). We selected the 328 elderly with impaired fasting glucose in Binhai new area of Tianjin as the research object. All subjects participated in objective examinations such as physical activity ability tests, blood tests and anthropometric examinations, and completed the questionnaire survey. Between baseline and 3-year outcome, 56 of the subjects with IFG at baseline have developed diabetes. After multivariate adjustments, we found that higher incidence of diabetes was associated with higher fasting plasma glucose (OR=9.30, 95%CI 2.84-30.48, P<0.01) and reduced grip strength/weight (OR=0.88, 95%CI 0.82-0.94, P<0.01). Moreover, the combination of higher fasting plasma glucose and lower grip strength/weight would lead to higher incidence of diabetes compared with higher fasting plasma glucose or lower grip strength/weight alone (P<0.05). In this study, high fasting plasma glucose and low muscle strength were associated with blood glucose worsening in three years in IFG patients. In addition to blood glucose levels, physical activity is also a risk factor for diabetes in older adults.
作者
王原原
万春晓
赵英
韩海津
刘新新
门艳军
Wang Yuanyuan;Wan Chunxiao;Zhao Ying;Han Haijin;Liu Xinxin;Men Yanjun(General Hospital of Tianjin Medical University,Tianjin 300052,China;Department of Rehabilitation Medicine,Tianjin Peking University Medical Offshore Oil Hospital,Tianjin 300452,China)
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2019年第9期765-769,共5页
Chinese Journal of Endocrinology and Metabolism
关键词
空腹血糖受损
肌肉力量
老年人
Impaired fasting glycaemia
Muscle strength
Elderly
