摘要
目的研究广州市≥50岁居民主动脉弓钙化（AAC）现患率及其相关特征。方法收集10413名年龄在≥50岁居民的一般资料，体格检查和实验室检查结果；用东芝KSO-15R型X光机拍摄10305名受检者胸部后前位X线平片，由2名高级放射科医师一起进行X线胸片AAC诊断，同时作独立阅片一致性可靠检验（Kappa值）。结果（1）2名高级放射科医师独立阅片对AAC诊断符合率为85．0％，一致性可靠检验Kappa值为0．68（P〈0．001），显示其AAC诊断一致性是可靠的；（2）10305名（男3064，女7349）受检者平均年龄男（640±6．0）岁，女（66．2±5．8）岁，文化程度以中学或以下为主，从事工人和农民职业占一半以上；（3）AAC检出率：为40．6％，女性（41．4％）高于男性（38．6％）；（4）AAC随年龄增加而明显增加（P〈0．001），但与职业无明显相关；（5）AAC主要发生于弓部（98．7％），长度〉10mm（57．6％）、宽度1～4mm（74．0％）占多数，提示≥50岁者AAC程度较为严重。结论广州市≥50岁者AAC检出率为40．6％，明显高于国外相关报道，程度也较严重，其原因及机理正在进一步探讨。
Objective To examine the prevalence and characteristics of aortic arch calcification （AAC） in residents aged 50 or over in Guangzhou, China. Methods Face-to-face interview, physical examination and laboratory tests were conducted on 10 413 Chinese adults aged 50 or over. Posterior-anterior plain chest X-ray radiographs were obtained from 10 305 subjects using a Toshiba KSO 15R machine . The radiographs were reviewed together by two radiologists while 300 radiographs were independently gone through by two radiologists to assess the agreement with Kappa coefficient method. Results The rate of agreement on Diagnosis for the two radiologists was 85.0 % and Kappa coefficient was 0.68,with P〈0. 001 which showed a moderate agreement between the two radiologists. Among the 10 305 subjects, there were 3064 men and 7349 women, with their mean age （ ＋ standard deviation） as 64.0 ± 6.0 and 66.2 ± 5.8, respectively. Most of them had educational level of middle school or below, and most of their occupations were factory or agricultural workers. The prevalence of AAC was 40.6 %. Women showed significantly higher prevalence rate than men（41.4% versus 38.6 %, P 〈 0. 001 ） and the prevalence of AAC increased significantly with age. Subjects with primary educational level or below had the highest prevalence of AAC. There was no significant association found between occupation and AAC prevalence. 98.7 % of the subjects with AAC occurred in aortic arch. Most AAC had a length of 10 mm or longer and a width from 1-4 mm, which indicated the severity of AAC among the subjects. Conclusion The prevalence of AAC among Guangzhou Biobank Cohort was about 40.6 % , higher than those reported in foreign studies, while most of the lesions were quite serious.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2007年第2期173-176,共4页
Chinese Journal of Epidemiology
基金
张承惠教授、焦书海主任负责本项研究的X线胸片诊断
广州市科技局、卫生局,香港大学科研教育基金委员会,英国伯明翰大学医学院对本研究提供资助,谨此致谢.
关键词
主动脉弓钙化
现患率
影像学特征
Aortic arch calcification
Prevalence
Imaging characteristics
