摘要
目的探讨糖尿病诊断中采用化学发光法测C肽、胰岛素的临床应用价值。方法选取本院50例糖尿病患者列为研究组,另选取同期健康人群50名列为对照组。抽取两组对象静脉血样本采用化学发光免疫分析法测定胰岛素和C肽指数,并采用放射免疫法测定对照组的C肽和胰岛素。比较两组对象餐前和餐后1~3 h C肽和胰岛素释放情况C肽和胰岛素测定情况,以及两种检测方法对对照组检验结果的影响。结果两组患者分别经过检查后可知,研究组餐前C肽以及3 h C肽值明显高于对照组,且餐前胰岛素以及餐后3 h胰岛素释放情况明显高于对照组(P<0.05)。结论在糖尿病诊断中,使用化学发光免疫分析法对C肽及胰岛素进行检测可用于临床,具有临床应用价值,也可帮助糖尿病分型,值得展开广泛推广。
Objective To explore the clinical value of chemiluminescence in the diagnosis of diabetes mellitus.Methods 50 patients with diabetes mellitus in our hospital were selected as the research group,and 50 healthy people in the same period were selected as the control group.Insulin and C-peptide index were measured by chemiluminescent immunoassay(CLIA)and C-peptide and insulin in control group were measured by radioimmunoassay(RIA).The levels of C-peptide and insulin release before and after meals were compared between the two groups,and the effects of the two methods on the results of the control group were also compared.Results After examination,the values of C-peptide and 3-hour C-peptide in the research group were significantly higher than those in the control group,and the releases of insulin before meal and 3-hour after meal were significantly higher than those in the control group(P<0.05).Conclusion Chemiluminescence immunoassay can be used to detect C-peptide and insulin in the diagnosis of diabetes mellitus.It has clinical value and can help to classify diabetes mellitus.It is worth spreading widely.
作者
彭志芳
Peng Zhifang(Department of Clinical Laboratory,Yichun Zhegan Friendship Hospital,Yichun,Jiangxi,336000,China)
出处
《当代医学》
2019年第28期37-39,共3页
Contemporary Medicine
关键词
糖尿病
化学发光法
C肽
胰岛素
Diabetes mellitus
Chemiluminescence
C-peptide
Insulin
