摘要
目的:探讨持续非卧床腹膜透析(CAPD)患者腹膜透析相关性腹膜炎(PDAP)发生的相关因素、分析腹膜炎的致病菌特点、药物敏感性和临床转归。方法:回顾性分析2012年5月至2017年10月福建医科大学附属龙岩第一医院肾内科收治的168例次PDAP患者的病原学、病原学特点、疗效以及转归。结果:PDAP最主要的相关因素是操作污染。168例次PDAP中132例次培养结果阳性。其中革兰阳性菌78例次(59.09%)、革兰阴性菌31例次(23.48%)、真菌14例次(10.6%)、混合感染9例次(6.82%)。结论:PDAP的发生率与操作不规范、营养不良密切相关,病原学仍以革兰阳性菌为主,真菌感染患者退出率高。
Objective:To investigate the factors related to the occurrence of peritoneal dialysis-associated peritonitis(PDAP)in patients undergoing continuous ambulatory peritoneal dialysis(CAPD),and analyze their pathogenic bacteria,drug sensitivity and clinical outcome.Methods:The etiology,pathogenic characteristics,efficacy and outcome of 168 patients with PDAP treated in our hospital were retrospectively analyzed.Results:The main factor related to PDAP was operational pollution.Among the 168 patients with PDAP,132 patients showed positive results in microbial culture,including 78 cases(59.09%)infected by gram-positive bacteria,31cases(23.48%)by gram-negative bacteria,14 cases(10.6%)by fungi and 9 cases(6.82%)by mixed infections.Conclusion:The incidence of PDAP is closely related to non-standard operation and malnutrition.Grampositive bacteria are still the main pathogens and the withdrawal rate of patients with fungal infection is high.
作者
邓金秀
王福珍
丘昭文
郭春花
林冲云
吴森超
DENG Jinxiu;WANG Fuzhen;QIU Zhaowen;GUO Chunhua;LIN Chongyun;WU Sengchao(Department of Nephrology,the 1st Hospital of Longyan affiliated to Fujian Medical University,Fujian Longyan 364000,China)
出处
《上海医药》
CAS
2019年第15期40-44,共5页
Shanghai Medical & Pharmaceutical Journal
关键词
腹膜透析
腹膜炎
致病菌
耐药性
peritoneal dialysis
peritonitis
pathogenic bacteria
drug sensitivity
