摘要
目的研究分析高血压脑出血行微创治疗的神经功能缺损评分与预后情况,为临床及时有效的处理高血压脑出血以及改善患者的预后情况,提供理论依据。方法 2017年2月至2018年2月期间,将100例到我院进行治疗的高血压脑出血患者作为研究对象,采集随机数字表将患者随机分成试验组(采用微创治疗)和内镜组(采用内镜手术进行治疗),各50例;比较两组患者围手术期的临床指标(手术时间、出血量、住院时间、血肿清除率、住院花费)、临床指标水平(NT-proBNP、GM-CSF、HMGB-1、AngⅡ、MIP-1α、PRA水平)、疗前后BI评分、SSS评分、MRS评分以及临床疗效的统计学差异。结果试验组患者手术时间、出血量、住院时间、血肿清除率、住院花费显著低于对照组患者(P<0. 05)。两组患者治疗前后NT-proBNP、GM-CSF、HMGB-1、AngⅡ、MIP-1α、PRA水平、BI评分、SSS评分、MRS评分差异显著(P<0. 05),随着时间迁移,NT-proBNP、GM-CSF、HMGB-1、MIP-1α、PRA水平、MRS评分呈现显著下降趋势,AngⅡ水平、BI评分、SSS评分呈现显著上升趋势。治疗后试验组NT-proBNP、GM-CSF、HMGB-1、AngⅡ、MIP-1α、PRA水平、MRS评分显著低于对照组,BI评分、SSS评分显著高于对照组。试验组患者临床疗效显著优于对照组患者,且有效率显著高于对照组患者(P<0. 05)。结论采用微创手术治疗高血压脑出血患者的神经功能缺损评分明显优于采取内镜手术的患者,不仅可以有效提高临床疗效,还可以改善临床指标和预后情况,值得临床推广。
Objective To study and analyze the neurological deficit scores and prognosis of patients with hypertensive cerebral hemorrhage treated with minimally invasive therapy,and to provide a theoretical basis for the timely and effective treatment of hypertensive cerebral hemorrhage and the improvement of the prognosis of patients. Methods One hundred patients with hypertensive cerebral hemorrhage who were treated in our hospital from February 2017 to February 2018 were selected as subjects and randomly divided into experimental group( treated with minimally invasive therapy) and endoscopic group( treated with endoscopic surgery) with random number tables,50 cases in each group. The perioperative clinical indicators( operation time,amount of bleeding,hospitalization time,hematoma clearance rate,hospitalization cost),clinical indicator levels( NT-pro BNP,GM-CSF,HMGB-1,Ang II,MIP-1α,PRA level),BI score before and after treatment,SSS score,MRS score,and statistical difference in clinical efficacy of the two groups were compared. Results The operation time,amount of bleeding,hospitalization time,hematoma clearance rate,and hospitalization cost in the experimental group were significantly lower than those in the control group( P<0. 05). There were significant differences in NT-proBNP,GM-CSF,HMGB-1,Ang II,MIP-1α,PRA level,BI score,SSS score,and MRS score between the two groups before and after treatment( P<0. 05). Over time,NT-proBNP,GM-CSF,HMGB-1,MIP-1α,PRA level and MRS score showed a significant downward trend,and Ang II level,BI score and SSS score showed a significant upward trend. After treatment,the NT-proBNP,GM-CSF,HMGB-1,Ang II,MIP-1α,PRA level and MRS scores in the experimental group were significantly lower than those in the control group,and the BI score and SSS score were significantly higher than those in the control group. The clinical efficacy of the experimental group was significantly better than that of the control group,and the effective rate was significantly higher than that of the control group( P<0
作者
谭宝东
崔连旭
赵庆顺
陆大鸿
彭四维
李昊旻
Tan Baodong;Cui Lianxu;Zhao Qingshun;Lu Dahong;Peng Siwei;Li Haomin(Department of Minimally Invasive and Spinal Neurosurgery,Foshan First People s Hospital,Foshan 528000 China)
出处
《锦州医科大学学报》
CAS
2019年第5期48-52,共5页
Journal of Jinzhou Medical University
关键词
高血压脑出血
微创治疗
神经功能缺损
预后情况
hypertensive cerebral hemorrhage
minimally invasive therapy
neurological deficit
prognosis
