摘要
目的探讨帕金森病采用低频重复经颅磁刺激对患者运动及执行功能的影响。方法选取2016年4月至2018年3月菏泽市第三人民院收治的94例帕金森病患者,按单盲法分为两组,每组47例。对照组采用多巴丝肼片、司来吉兰片治疗,观察组在此基础上采用低频重复经颅磁刺激治疗。治疗后2个月,比较两组运动功能、自主神经功能、执行功能。结果治疗后,两组运动功能、自主神经功能评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组快速语词流畅性测验、画钟测验、连线测验评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论在常规药物治疗基础上,低频重复经颅磁刺激治疗不仅可改善帕金森病患者自主神经功能和运动功能,还可提升其执行功能。
Objective To investigate the effects of low-frequency repetitive transcranial magnetic stimulation on motor function and executive function in patients with Parkinson’s disease. Methods Ninety-four patients with Parkinson’s disease admitted to the Third People’s Hospital of Heze from April 2016 to March 2018 were selected and divided into two groups by single blind method, with 47 patients in each group. The control group was treated with levodopa and benserazide hydrazine tablets and selegeran tablets. The observation group was treated with low-frequency repetitive transcranial magnetic stimulation based on the treatment for control group. After 2 months of treatment, motor function, autonomic nervous function and executive function were compared between the two groups. Results After treatment, motor function (UPDRS Ⅲ), autonomic nervous function (SCOPA - AUT) score of the two groups was lower, and the observation group had lower scores than the control group (P<0.05). After treatment, rapid verbal retrieve, clock drawing test and trail marking test scores of the two groups were higher than those before treatment, and the differences between the two groups were statistically significant (P<0.05). Conclusions On the basis of conventional drug therapy, low-frequency repetitive transcranial magnetic stimulation can not only improve autonomic nervous function and motor function, but also enhance executive function in patients with Parkinson’s disease.
作者
齐美红
Qi Meihong(Department of Psychiatric Rehabilitation,the Third People’s Hospital of Heze,Heze 274000,China)
出处
《中国实用医刊》
2019年第18期92-94,共3页
Chinese Journal of Practical Medicine
关键词
帕金森病
低频重复经颅磁刺激
运动功能
执行功能
Parkinson's disease
Low-frequency repetitive transcranial magnetic stimulation
Motor function
Executive function
