摘要
多数癫痫在儿童期起病,可造成严重智力及心理发育障碍。多数癫痫患者经过正规抗癫痫药物治疗,可以控制癫痫发作,但仍有20%~30%的癫痫患者经过长期药物治疗不能控制发作,为难治性癫痫,需要手术治疗。进行详细的术前评估、明确致痫灶是手术治疗的关键。随着对癫痫认识的不断加深、影像学检查技术的进步,促使癫痫手术评估的变化。现就目前儿童难治性癫痫手术评估的一些方法及进展进行综述。
Epilepsy mostly starts in childhood and can cause severe mental disorders.Treatment with antiepileptic drugs is effective in most patients,but 20%-30%of the patients continue to have uncontrolled seizures despite medical therapy,these are called drug-resistant epilepsy and need surgical treatment.Critical to discussion of surgical therapy are detailed presurgical evaluation and the lateralization and localization of epileptogenic zone.With deepening of the knowledge of epilepsy and progress of imaging technology,the evaluation of epilepsy surgery is changing gradually.Now,some methods and advances of surgical evaluation for children with drug-resistant epilepsy are reviewed.
作者
许文全
赵瑞
李昊
Xu Wenquan;Zhao Rui;Li Hao(Department of Neurosurgery,Children′s Hospital of Fudan University,Shanghai Medical College,Fudan University,National Center for Children′s Health,Shanghai 201102,China)
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2019年第18期1433-1436,共4页
Chinese Journal of Applied Clinical Pediatrics
关键词
难治性癫痫
术前评估
儿童
Drug-resistant epilepsy
Presurgical evaluation
Child
