摘要
烧伤的发生、发展及预后是一个复杂的病理生理进程,涉及众多的器官和系统。随着科技的发展和治疗理念的更新,越来越多的新材料、新设备、新方法应用于烧伤的诊治。在解剖结构和生理功能上与人类接近的动物,是研究烧伤问题的最合适模型。目前研究烧伤的动物模型已经发展到可以对烧伤不同方面的情况进行模拟。这些模型在阐明烧伤的病理生理机制,为人类研究新的治疗干预方法、新的材料等方面提供了重要的基础支持。了解这些动物模型的优点和局限性,对于研究与人类相关的临床治疗措施和材料而言是必不可少。
The occurrence, development, and prognosis of burn is a complicated pathophysiological process involving many organs and systems. With the development of science and technology and update of treatment concept, more and more new materials, new equipments, and new methods are applied to the diagnosis and treatment of burn. Animals similar to humans in anatomical structure and physiological function are the ideal models for research of burn. Nowadays, animal models of burn have been developed to simulate different aspects of burn. These models provide important essential support for elucidating the pathophysiological mechanism of burns and exploring new therapeutic interventions and materials for human beings. Understanding the advantages and limitations of these animal models is essential for the research of burn.
作者
张永存
王亮
鲁晋
周浩
唐洪泰
Zhang Yongcun;Wang Liang;Lu Jin;Zhou Hao;Tang Hongtai(Burn Institute of PLA,Department of Burn Surgery,the First Affiliated Hospital,Naval Medical University,Shanghai 200433,China)
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2019年第9期692-696,共5页
Chinese Journal of Burns
基金
国家自然科学基金(81372057)
上海市科委科研计划(13DZ1942707).
关键词
烧伤
模型
动物
瘢痕
切痂
削痂
Burns
Models, animal
Cicatrix
Escharectomy
Tangential excision
