摘要
目的调查湖南省听力障碍儿童慢性肾脏病(CKD)的患病情况。方法运用横断面研究,采用多阶段整群抽样方法共抽取1 500名儿童作为研究样本,现场进行问卷调查、体格检查、实验室检查。结果 1 500名儿童中,纳入资料完整的儿童1 459名。CKD患病43例,患病率为2.95%,其中< 7岁组患病率(5.8%,35/604)显著高于7~14岁组(0.9%,8/855)(P < 0.05)。43例CKD患儿中,表现为蛋白尿31例(72%),表现为血尿27例(63%),表现肾小球滤过率下降11例(26%)。43例CKD患儿中,CKD 1、2、3a、3b、4、5期患病例数分别为13、19、5、3、3、0例,分别占30%、44%、12%、7%、7%、0%。CKD患病率随听力障碍程度加重而升高(P < 0.01)。结论湖南省听力障碍儿童中CKD的患病率较高,大部分处于CKD早期,学龄前期儿童多见。听力障碍程度与CKD的患病率相关。
Objective To investigate the prevalence of chronic kidney disease(CKD) among the children with hearing disorder in Hunan province, China. Methods In this cross-sectional study, the multi-stage cluster sampling method was used to select 1 500 children as subjects. Questionnaire surveys, physical examinations, and laboratory examinations were performed on the spot. Results Among the 1 500 children, 1?459 with complete data were included in analysis. Among the 1 459 children, 43 had CKD, with a prevalence rate of 2.95%. The <7 years group had a significantly higher prevalence rate than the 7-14 years group [5.8%(35/604) vs 0.9%(8/855);P<0.05]. Among the 43 children with CKD, 31(72%) had proteinuria, 27(63%) had hematuria, and 11(26%) had a decreased glomerular filtration rate. Among the 43 children with CKD, stage 1, 2, 3 a, 3 b, 4, and 5 CKD accounted for 30%(13 cases), 44%(19 cases), 12%(5 cases), 7%(3 cases), 7%(3 cases), and 0%(0 case) respectively. The prevalence rate of CKD increased with the severity of hearing disorder(P<0.01). Conclusions The prevalence rate of CKD is higher among the children with hearing disorder in Hunan province. Most children have early-stage CKD. CKD is commonly seen in preschool children. Severity of hearing disorder is associated with the prevalence of CKD.
作者
程相洋
朱一枫
罗淑
贺艳
王湘川
CHENG Xiang-Yang;ZHU Yi-Feng;LUO Shu;HE Yan;WANG Xiang-Chuan(Department of Nephrology, Second Affiliated Hospital of Hunan Normal University/921 Hospital of the People's Liberation Army of China, Changsha 410003, China)
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2019年第9期915-918,共4页
Chinese Journal of Contemporary Pediatrics
基金
湖南省残疾人联合会项目（2017XK010）
关键词
慢性肾脏病
听力障碍
患病率
儿童
Chronic kidney disease
Hearing disorder
Prevalence rate
Child
