摘要
目的探讨延续性护理对慢性肾脏病(CKD) 3~5期非透析患者估算肾小球滤过率(r GFR)及钙、磷、血清全段甲状旁腺激素(i PTH)的影响。方法选取2016年5月至2017年5月在我院肾内科就诊的CKD 3~5期非透析患者151例为研究对象,按入组先后顺序分为观察组70例和对照组81例。两组患者住院期间均给予系统的健康教育,出院后对照组给予常规健康指导,观察组在此基础上给予为期1年的延续性护理。比较两组出院1年后e GFR及钙、磷、i PTH情况。结果延续性护理1年后,3B期观察组e GFR无明显变化,而对照组e GFR明显下降,两组间比较差异无统计学意义(P>0.05);对照组血钙水平也明显下降并与观察组比较差异有统计学意义(P<0.05);4期两组e GFR均有所下降,但差异无统计学意义(P>0.05)。i PTH水平均有所上升,但对照组更明显(P<0.05)。结论延续性护理可以改善3B期钙的代谢,改善4期i PTH的代谢,对3B期CKD患者e GFR有延缓趋势,但仍需进一步的深入研究;对磷的代谢影响不大。
Objective To explore The effect of continuous nursing on estimating glomerular filtration rate (eGFR)and calcium, phosphorus and serum intact parathyroid hormone(iPTH) in non-dialysis patients with chronic kidney disease(CKD) 3~5 stages.Methods We selected 151 cases of non-dialysis patients with CKD 3~5 stages who were admitted to our department of nephrology from May 2016 to May 2017 as a study object.They were divided into observation group (70 cases) and control group (81 cases).The patients of both were given systematic health education during hospitalization, and the control group was given routine health guidance after discharge, and the observation group was given a one-year continuous nursing on this basis of the control group.The eGFR and calcium, phosphorus and iPTH were compared between the two groups after one year of discharge.Results After 1 year of continuous care, there was no significant change in eGFR of the stage 3B in observation group, but the eGFR in the control group decreased significantly.There was no statistical significance in the comparative difference between the two groups( P >0.05).The blood calcium level in the control group also decreased significantly and was different from the observation group, there was statistical significance in the comparative difference between the two groups(P<0.05);The eGFR of 4 stages decreased in both groups, but the difference was not statistical significance( P >0.05).The level of iPTH increased, but the control group was more obvious(P<0.05).Conclusion Continuous nursing could improve the metabolism of calcium in stage 3B, improve the metabolism of stage 4 iPTH, and delay the eGFR in patients with stage 3B CKD, but further research was needed;it had little effect on the metabolism of phosphorus.
作者
钟晓琴
祝胜朗
王莉
陈结慧
彭红云
蒋莹
朱爱军
ZHONG Xiao-qin;ZHU Sheng-lang;WANG Li;CHEN Jie-hui;PENG Hong-yun;JIANG Ying;ZHU Ai-jun
出处
《护理实践与研究》
2019年第17期48-51,共4页
Nursing Practice and Research
基金
广东省深圳市南山区2016年度区级课题计划资助项目(南科研卫2016031)
关键词
延续性护理
慢性肾脏病
估算肾小球滤过率
血清全段甲状旁腺激素
Continuous nursing
Chronic kidney disease
Estimating glomerular filtration rate
Serum intact parathyroid hormone
