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维生素A的毒理学研究进展 被引量:7

Research progress in toxicology of vitamin A
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摘要 维生素A作为人体必需的维生素具有很多生理功能.维生素A作为一种预防疾病的手段,伴随其产生的问题越来越多,维生素A摄入过多造成急性或慢性中毒、肝脏毒性、生殖毒性、发育毒性及致畸性等.维生素A的毒性作用应引起人们的关注.本文总结了维生素A的功能及代谢,重点关注了过量维生素A及其代谢物对细胞或个体造成的毒害作用. Vitamin A has many physiological functions as an essential vitamin.Vitamin A as a means of preventing diseases,the problems that followed are increasing.Excessive intake of vitamin A causes acute or chronic poisoning,liver toxicity,reproductive toxicity,developmental toxicity and teratogenicity.The toxic effects of vitamin A should also attract people's attention.This paper summarized the function and metabolism of vitamin A,focusing on the toxic effects of excess vitamin A and the metabolites on cells or individuals.
作者 王亚莉 耿越 WANG Ya-Li;GENG Yue(Key Laboratory of Food Nutrition and Safety of SDNU,Provincial Key Laboratory of Animal Resistant Biology,College of Life Science,Shandong Normal University,Jinan 250014,China)
出处 《食品安全质量检测学报》 CAS 2019年第15期5019-5023,共5页 Journal of Food Safety and Quality
关键词 维生素A 毒性作用 维生素A代谢 视黄酸 vitamin A toxic effects vitamin A metabolism retinoic acid
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