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输卵管妊娠腹腔镜保守手术联合甲氨蝶呤局部注射预防持续性异位妊娠效果 被引量:3

Effect of Conservative Laparoscopic Surgery Combined with Local Injection of Methotrexate for Prevention of Persistent Ectopic Pregnancy in Tubal Pregnancy
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摘要 目的:观察输卵管妊娠腹腔镜保守手术联合甲氨蝶呤局部注射预防持续性异位妊娠效果。方法:选取笔者所在医院2016年1月2日-2018年5月3日收治的76例输卵管妊娠患者,采用随机数字表法将76例患者分为手术组(38例)与联合注射组(38例),对比两组术后各个阶段的血清β-hCG下降率、持续性异位妊娠及其他并发症发生情况。结果:联合注射组各个阶段血清β-hCG下降率、持续性异位妊娠发生情况均优于手术组,差异均有统计学意义(P<0.05);两组不良反应发生情况比较差异无统计学意义(P>0.05)。结论:在实施输卵管妊娠腹腔镜保守手术同时对患者进行甲氨蝶呤局部注射,可显著降低患者的血清β-hCG值,降低持续性异位妊娠的发生风险,对于改善患者预后有重要意义。 Objective:To observe the effect of conservative laparoscopic surgery combined with local injection of Methotrexate in the prevention of persistent ectopic pregnancy.Method:A total of 76 tubal pregnancy treated in my hospital from January 2,2016 to May 3,2018 were selected,and were divided into the operation group(38 cases) and the combined injection group(38 cases) by random numerical table method.The serum β-hCG rate of decline at each stage after operation,persistent ectopic pregnancy and other complications were compared between the two groups.Result:The rate of decline of serum β-hCG in the combined injection group was significantly lower than that in the operation group,and the incidence of persistent ectopic pregnancy was significantly higher than that in the operation group(P<0.05).There was no significant difference in the occurrence of adverse reactions between the two groups(P>0.05).Conclusion:The local injection of Methotrexate in the conservative operation of laparoscopic tubal pregnancy can significantly reduce the serum β-hCG value and reduce the risk of persistent ectopic pregnancy,which is of great significance for improving the prognosis of patients.
作者 吴丽美 WU Limei(Fujian Funeng Group General Hospital,Fuzhou 350001,China)
出处 《中外医学研究》 2019年第23期123-124,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 输卵管妊娠 腹腔镜保守手术治疗 甲氨蝶呤 持续性异位妊娠 局部注射预防效果 Tubal pregnancy Conservative laparoscopic surgery Methotrexate Persistent ectopic pregnancy Local injection prevention effect
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