摘要
目的评估陶瓷人工骨填充成人良性骨肿瘤和瘤样病变刮除后骨缺损的疗效及潜在并发症。方法回顾性分析2013年1月至2017年6月在本院行病灶刮除植骨的良性骨肿瘤和瘤样病变患者资料。共纳入32例,男17例,女15例,平均年龄34.2(18~57)岁。平均病变体积25.0(0.1~169.6)cm^3。平均植入人工骨4.0 g(0.2~10 g)根据X线片表现以改良Neer法评估骨愈合、材料吸收和病变复发情况。Goslings和Gouma法评估术后并发症。结果平均随访1.8(0.5~6)年,Neer分级6例Ⅰ级,26例Ⅱ级。2年以上随访11例,7例骨皮质增厚,3例材料完全吸收。1例手部内生软骨瘤术后发生骨折,并发症分级为Ⅰ级。随访期间未发现病变复发。所有患者均恢复肢体正常功能。结论该人工骨填充成人良性骨肿瘤和瘤样病变刮除后骨缺损效果可靠,并发症少,但材料吸收较慢。
Objective To evaluate the efficacy and potential complication associated with the use of bioceramic artificial bone substitute following curettage of benign bone tumors and tumor-like lesions in adult patients. Methods Clinical data of patients who were treated with curettage and refilling of bone cavity at our orthopedic center from January 2013 to June2017 were retrospectively analyzed. There were 17 males and 15 females with a mean age of 34.2(18-57) years. The estimated mean volume was 25.0(0.1-169.6) cm3. The mean graft mass used to fill each lesion was 4.0 g(0.2-10 g).Postoperative radiological changes including bone healing, graft resorption and lesion recurrence were evaluated by a modified Neer’s classification. The incidence of complication was recorded and assessed using Goslings and Gouma’s scale. Results At a mean follow up of 1.8(0.5-6) years, six defects were graded as Neer’s gradeⅠand 26 were Neer’s grade Ⅱ. Eleven patients were followed up for more than 2 years with either signs of cortex thicker than normal in 7 patients or complete graft resorption in 3 patients. One postoperative fracture occurred after removal of an enchondroma of in the hand, which was graded as grade Ⅰ complication. No lesion occurrence was observed during the observation period. Recovery of limb function was normal in all patients. Conclusion The bioceramic artificial bone seems to be a reliable bone substitute for refilling bone cavity following curettage of benign bone tumors and tumor-like lesions in adult patients with a low complication rate. However, delayed resorption should be expected.
作者
潘朝晖
赵玉祥
薛山
李洪飞
高朋
王剑利
Pan Zhaohui;Zhao Yiixiang;Xue Shan(Orthopedic Institute of Chinese PLA, Hospital of the 80th Group Army, Weifang Shandong, 261021, China)
出处
《生物骨科材料与临床研究》
CAS
2019年第4期5-9,共5页
Orthopaedic Biomechanics Materials and Clinical Study
关键词
良性骨肿瘤
瘤样病变
骨缺损
生物陶瓷人工骨
并发症
Benign bone tumor
Tumor-like lesion
Bone defect
Bioceramic artificial bone
Complication
