摘要
艾滋病病毒(HIV)包含HIV-1和HIV-2两种类型。到目前为止,在HIV感染的临床筛查中,发现的感染类型绝大多数为HIV-1型,极少数为HIV-2型。国外HIV-2型主要集中在西非地区,我国偶有发现HIV-2型的感染病例。由于临床中遇到的HIV-2型感染病例数较少,所以对HIV的研究多集中在了HIV-1型上。随着全球化的推进和人员交流日益频繁,HIV-2型感染的风险正在不断增加,临床上遇到的HIV-2型感染病例也会增加,应引起科研人员和临床医生足够的重视。本文从HIV-2型感染的流行病学、诊断方案及抗病毒防治措施等几个方面进行探讨,以期为我国HIV-2型的预防及诊治策略的制定提供参考意见。
Human immunodeficiency virus(HIV) is divided into two types, HIV-1 and HIV-2. To date, HIV-1 has accounted predominately in the clinical screening of HIV infection, while there are few cases of HIV-2 discovered. HIV-2 isolate is mainly prevalent in the West Africa, and its infection has occasionally been found in China. Because of the small number of HIV-2 infections encountered in the clinic, the researches mainly focus on HIV-1. However, the globalization is accelerating exchanges around the world and the risk of HIV-2 infection is increasing. Therefore, there will be an increase in the number of HIV-2-infected patients, which should get sufficient attention by researchers and clinicians. This article will review the epidemiology, diagnosis, antiretroviral treatment of HIV-2, in order to provide advice for prevention and therapeutic strategies against HIV-2 infection in China.
作者
粟斌
吴昊
张彤
SU Bin;WU Hao;ZHANG Tong(Center for Infectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2019年第7期756-759,共4页
Chinese Journal of Aids & STD
基金
国家自然科学基金项目(81772165)
国家“十三五”科技重大专项(2017ZX10202102-005-003,2017ZX10202101-004-001)
艾滋病研究北京市重点实验室(BZ0089)~~
关键词
2型艾滋病病毒
流行病学
诊疗策略
防治措施
HIV-2
epidemiology
diagnosis and treatment strategies
prevention measures
